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Baclofen

What is Baclofen

Baclofen is a muscle relaxant and an antispastic agent. The exact way that Baclofen works is unknown.

Baclofen is used to relieve the muscle spasms, pain, and muscular rigidity associated with multiple sclerosis.

Baclofen may also be used for purposes other than those listed in this medication guide.

General medical information about Baclofen

Use caution when driving, operating machinery, or performing other hazardous activities. Baclofen may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.

Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking Baclofen.

Do not stop taking Baclofen suddenly. Stopping suddenly may cause seizures or hallucinations. Your doctor will want to gradually reduce you dose.

What you should find out before taking Baclofen

Before taking this medication, tell your doctor if you have:
- kidney disease or
- epilepsy or another seizure disorder.

You may not be able to take Baclofen, or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above.

Baclofen is in the FDA pregnancy category C. This means that it is not known whether Baclofen will harm an unborn baby. Do not take Baclofen without first talking to your doctor if you are pregnant.

It is also not known whether Baclofen passes into breast milk. Do not take Baclofen without first talking to your doctor if you are breast-feeding a baby.

How should take Baclofen

Take Baclofen exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water.

You can take Baclofen with or without food.

Do not stop taking Baclofen suddenly. Stopping suddenly could cause seizures or hallucinations. Talk to your doctor first if you need to stop taking this medication.

Store Baclofen at room temperature away from moisture and heat.

If you miss a dose:

Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of this medication.

What happens if you overdose:

Seek emergency medical treatment.

Symptoms of a Baclofen overdose include vomiting, weakness, drowsiness, slow breathing, seizures, unusual pupil size, and coma.

Avoid while taking Baclofen

Use caution when driving, operating machinery, or performing other hazardous activities. Baclofen may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.

Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking Baclofen.

Possible side effects of Baclofen

If you experience any of the following serious side effects, stop taking Baclofen and seek emergency medical attention:
- an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);
- seizures; or
- an irregular heartbeat.

Other, less serious side effects are more likely to occur. Continue to take Baclofen and talk to your doctor if you experience any of the following:
- drowsiness, dizziness, weakness, or unusual fatigue;
- a headache;
- constipation;
- stuffy nose;
- blurred vision;
- a rash; or
- frequent urination.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect Baclofen

Many drugs can increase the effects of Baclofen, which can lead to heavy sedation. Before taking this medication, tell your doctor if you are taking any of the following medicines:
- antihistamines such as brompheniramine (Dimetane, Bromfed, others), chlorpheniramine (Chlor-Trimeton, Teldrin, others), azatadine (Optimine), clemastine (Tavist), and many others;
- narcotics (pain killers) such as meperidine (Demerol), morphine (MS Contin, MSIR, others), propoxyphene (Darvon, Darvocet), hydrocodone (Lorcet, Vicodin), oxycodone (Percocet, Percodan), fentanyl (Duragesic), and codeine (Fiorinal, Fioricet, Tylenol #3, others);
- sedatives such as phenobarbital (Solfoton, Luminal), amobarbital (Amytal), and secobarbital (Seconal);
- phenothiazines such as chlorpromazine (Thorazine), fluphenazine (Prolixin), mesoridazine (Serentil), perphenazine (Trilafon), prochlorperazine (Compazine), thioridazine (Mellaril), and trifluoperazine (Stelazine); or
- antidepressants such as doxepin (Sinequan), imipramine (Tofranil), nortriptyline (Pamelor), fluoxetine (Prozac), paroxetine (Paxil), sertraline (Zoloft), phenelzine (Nardil), and tranylcypromine (Parnate).

Drugs other than those listed here may also interact with Baclofen. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

All prescription drugs:

A
abilify accupril accutane acetaminophen aciphex actifed actonel actos acyclovir adalat adderall adipex advair advil albuterol alesse aleve allegra allopurinol amaryl ambien amiodarone amitriptyline amoxicillin amoxil amphetamine anacin aprazolam aricept asacol aspirin atenolol ativan atorvastatin atrovent augmentin avandia avapro avastin avelox azmacort
B
baclofen
bactrim bactroban baycol benadryl bextra biaxin boniva bontril buspar buspirone
C
caduet campral camptosar capoten captopril cardizem cardura carisoprodol casodex catapress cefzil celebrex celexa cellcept cephalexin cialis cipro ciprodex clarinex claritin climara clindamycin clonazepam clonidine codeine codeprex combivent combivir concerta copaxone coreg coricidin cotrim coumadin cozaar crestor cubicin cyclobenzaprine cymbalta
D
darvocet demerol depakote desogen detrol dextromethorphan diazepam diclofenac didrex diflucan digoxin dilantin diltiazem dimetapp diovan diprivan ditropan doxazosin doxycycline drixoral duragesic dyazide
E
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F
fabrazyme famotidine fazaclo fenofibrate fioricet fiorinal flexeril flomax flonase flovent fluoxetine fosamax fosrenol furosemide  
G
gabapentin gamimune gemfibrozil gemzar glipizide glucophage glucotrol glucovance glyburide glyburide guaifenesin guaifenex 
H
herceptin humalog humira hydroxyzine hyzaar  
I
ibuprofen imdur imitrex imodium inderal insulin integrilin iressa 
K
kaletra keflex kenalog keppra ketek klonopin kytril  
L
lamictal lamisil lanoxin lantus lasix lescol levaquin levitra levothyroxine levoxyl lexapro lidoderm lipitor lisinopril lithium lorazepam lortab lotensin lotrel lotrisone lovenox lupron luveris  
M
macrobid magnevist meclizine medroxyprogesterone meridia metformin methadone methamphetamine methotrexate methylphenidate methylprednisolone metoclopramide metoprolol metronidazole miacalcin minocycline mobic monopril morphine motrin myfortic  
N
naproxen nasacort nasonex natrecor neulasta neupogen neurontin nexium nifedipine nitrofurantoin norco nortriptyline norvasc  
O
omeprazole omnicef orthovisc oxybutynin oxycodone oxycontin oxytrol  
P
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R
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S
sanctura seasonale sensipar serevent seroquel serzone singulair skelaxin soma somavert sonata spiriva spironolactone strattera striant sustiva synagis synthroid 
T
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U
ultane ultracet ultram uroxatral
V
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W
warfarin wellbutrin  
X
xalatan xanax xenical xifaxan xolair xopenex xyrem  
Y
yasmin 
Z
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