What is Celebrex
is in a class of drugs called nonsteroidal anti-inflammatory
drugs (NSAIDs). Celebrex works by reducing substances that
cause inflammation, pain, and fever in the body.
is used to reduce pain, inflammation, and stiffness caused
by osteoarthritis and rheumatoid arthritis. Celebrex is also
used to reduce the number of adenomatous colorectal polyps
in familial adenomatous polyposis (FAP), to treat acute pain,
and to treat pain associated with menstruation.
may also be used for purposes other than those listed in this
General medical information about Celebrex
Notify your doctor immediately if you develop abdominal
pain, tenderness, or discomfort; nausea; bloody vomit; bloody,
black, or tarry stools; unexplained weight gain; swelling
or water retention; fatigue or lethargy; a skin rash; itching;
yellowing of the skin or eyes;"flu-like" symptoms;
or unusual bruising or bleeding. These symptoms could be
early signs of dangerous side effects.
What you should find out before taking
Do not take Celebrex without first talking to your
doctor if you have
- had an allergic reaction to
a sulfa-based medicine such as sulfamethoxazole (Bactrim,
Septra, Gantanol, and others), sulfisoxazole (Gantrisin),
and others; or
- experienced asthma, hives, or an
allergic reaction after taking aspirin or another NSAID
such as ibuprofen (Motrin, Advil, Nuprin, and others), naproxen
(Aleve, Naprosyn, Anaprox), ketoprofen (Orudis KT, Orudis,
Oruvail), diclofenac (Voltaren, Cataflam), diflunisal (Dolobid),
etodolac (Lodine, Lodine XL), fenoprofen (Nalfon), flurbiprofen
(Ansaid), indomethacin (Indocin), ketorolac (Toradol), meloxicam
(Mobic), nabumetone (Relafen), oxaprozin (Daypro), piroxicam
(Feldene), sulindac (Clinoril), or tolmetin (Tolectin).
You may experience a similar reaction to Celebrex.
Before taking Celebrex, tell your doctor if you
- drink alcohol;
- have an ulcer or
bleeding in the stomach;
- have liver disease;
have kidney disease;
- have asthma;
congestive heart failure;
- have fluid retention;
- have heart disease;
- have high blood pressure;
- have a coagulation (bleeding) disorder or are taking
an anticoagulant (blood thinner) such as warfarin (Coumadin);
- are taking a steroid medicine such as prednisone
(Deltasone and others), methylprednisolone (Medrol and others),
prednisolone (Prelone, Pediapred, and others), and others.
You may not be able to take Celebrex, or you may
require a dosage adjustment or special monitoring during
treatment if you have any of the conditions, or are taking
any of the medicines, listed above.
Celebrex is in
the FDA pregnancy category C. This means that it is not
known whether it will harm an unborn baby. Celebrex should
not be taken late in pregnancy (the third trimester) because
it may affect the formation of the baby's heart. Do not
take Celebrex without first talking to your doctor if you
It is not known whether Celebrex passes
into breast milk. Do not take Celebrex without first talking
to your doctor if you are breast-feeding.
has not been studied in children younger than 18 years of
If you are over the age of 65 years, you may
be more likely to experience side effects from Celebrex.
You may require a lower dosage or special monitoring during
How should take Celebrex Take Celebrex exactly as directed by your doctor.
If you do not understand these instructions, ask your pharmacist,
nurse, or doctor to explain them to you.
dose with a full glass of water.
Celebrex can be
taken with or without food or milk. Your doctor may recommend
taking higher doses of Celebrex with food. Follow your doctor's
Store Celebrex at room temperature
away from moisture and heat.
If you miss a dose: Take the missed dose as soon as you remember. If
it is almost time for the next dose, skip the dose you missed
and take only the next regularly scheduled dose as directed.
Do not take a double dose of this medication unless your
doctor directs otherwise.
What happens if you overdose: Seek emergency medical attention.
of a Celebrex overdose include drowsiness, nausea, vomiting,
stomach pain, dizziness, headache, ringing in the ears,
blurred vision, little or no urine production, slow breathing,
Avoid while taking Celebrex There are no restrictions on food, beverages, or
activity while taking Celebrex unless otherwise directed
by your doctor.
Possible side effects of Celebrex If you experience any of the following serious side
effects, stop taking Celebrex and seek medical treatment
or call your doctor immediately:
- an allergic reaction
(difficulty breathing; closing of your throat; swelling
of your lips, tongue, or face; or hives);
pain, tenderness, or discomfort;
- bloody, black,
or tarry stools;
- nausea or heartburn;
- unexplained weight gain;
swelling or water retention;
- unusual fatigue or
- a skin rash or itching;
of your skin or eyes;
- "flu-like" symptoms;
- unusual bruising or bleeding.
less serious side effects may be more likely to occur. Continue
to take Celebrex and talk to your doctor if you experience
- flatulence or diarrhea;
Side effects other
than those listed here may also occur. Talk to your doctor
about any side effect that seems unusual or that is especially
What other drugs will affect Celebrex Before taking Celebrex, tell your doctor if you are
taking any of the following drugs:
- aspirin or another
salicylate (form of aspirin) such as salsalate (Disalcid),
choline salicylate-magnesium salicylate (Trilisate, Tricosal,
others), and magnesium salicylate (Doan's, Bayer Select
Backache Formula, others);
- an over-the-counter
cough, cold, allergy, or pain medicine that contains aspirin,
ibuprofen, naproxen, or ketoprofen;
- a diuretic
(water pill) such as furosemide (Lasix), hydrochlorothiazide
(HydroDiuril, others), chlorothiazide (Diuril, others),
chlorthalidone (Hygroton, Thalitone), and others;
an angiotensin-converting-enzyme inhibitor (ACE inhibitor)
such as benazepril (Lotensin), captopril (Capoten), enalapril
(Vasotec), lisinopril (Prinivil, Zestril), moexipril (Univasc),
quinapril (Accupril), and others;
- a steroid medicine
such as prednisone (Deltasone and others), methylprednisolone
(Medrol and others), prednisolone (Prelone, Pediapred, and
others), and others;
- an anticoagulant (blood thinner)
such as warfarin (Coumadin);
- lithium (Eskalith,
Lithobid, others); or
- fluconazole (Diflucan).
You may not be able to take an Celebrex, or you may require
a dosage adjustment or special monitoring during treatment
if you are taking any of the medicines listed above.
other than those listed here may also interact with Celebrex.
Talk to your doctor and pharmacist before taking any prescription
or over-the-counter medicines, including herbal products.