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Copaxone

What is Copaxone

Copaxone is a combination of four amino acids (proteins). It is believed to affect the immune system.

Copaxone is used to decrease the frequency of relapses in patients with relapsing-remitting multiple sclerosis (MS).

Copaxone may also be used for purposes other than those listed in this medication guide.

General medical information about Copaxone

Copaxone is injected subcutaneously (under the skin). Your doctor or nurse will give you detailed instructions on how and where to inject Copaxone. Do not administer an injection if you are unsure how to properly do so, how much to inject, or how often to inject the medication. Call your doctor, nurse, or pharmacist to go over the instructions with you.

What you should discuss with your doctor before using Copaxone

Do not use Copaxone if you have an allergy to mannitol.

Before using this medication, tell your doctor if you have any other illness or if you take any other medicines. You may not be able to take Copaxone, or you may require a dosage adjustment or special monitoring during treatment.

Copaxone is in the FDA pregnancy category B. This means that it is not expected to be harmful to an unborn baby. Do not use this medication without first talking to your doctor if you are pregnant or could become pregnant during treatment.

It is not known whether Copaxone passes into breast milk. Do not use this medication without first talking to your doctor if you are breast-feeding a baby.

How should you use Copaxone

Use Copaxone exactly as directed by your doctor. If you do not understand these directions, ask your doctor, nurse, or pharmacist to explain them to you.

Copaxone is injected subcutaneously (under the skin). Your doctor or nurse will give you detailed instructions on how and where to inject Copaxone. Do not administer an injection if you are unsure how to properly do so, how much to inject, or how often to inject the medication. Call your doctor, nurse, or pharmacist to go over the instructions with you.

Do not use any medication that is discolored or that has particles in it.

A prefilled syringe package should be allowed to stand at room temperature for 20 minutes to allow the solution to warm up to room temperature. To prevent the loss of medication, do not try to expel any air that is in the prefilled syringe before injecting the medication.

Wash and dry the hands before preparing or administering an injection.

To reconstitute the powdered form of Copaxone, add the diluent provided to the powdered material using a syringe as directed. Gently swirl the mixture and allow the solid material to completely dissolve at room temperature. Use the mixture immediately after mixing.

The premixed or reconstituted medicine should be injected into the skin of the thighs, back of the hips, back of the upper arms, or abdomen (about 2 inches on either side of the bellybutton). Rotate the injection site as directed. Use each injection site only once every 7 days. Injections should be administered at about the same time each day.

Do not change your dose or stop using this medication without first talking to your doctor.

The vials and prefilled syringes are designed for a single use only. Throw away any unused medication after each injection.

Never reuse a needle or syringe. Dispose of all needles and syringes in an appropriate, puncture-resistant disposal container.

Store the prefilled syringes and brown vials of Copaxone in the refrigerator at 36 to 46 degrees Fahrenheit (2 to 8 degrees Celsius). In extenuating circumstances, when refrigeration may not be available, the product may be allowed to reach room temperature, 59 to 86 degrees Fahrenheit (15 to 30 degrees Celsius) for up to one week. Avoid exposure to higher temperatures or intense light. Store the clear vials of the diluent (labeled "Sterile Water for Injection") at room temperature.

If you miss a dose:

Inject the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the dose you missed and use only the next regularly scheduled dose. Do not inject a double dose of this medication unless otherwise directed.

What happens if you overdose:

Seek emergency medical attention.

Symptoms of a Copaxone overdose are not known.

What should you avoid while using Copaxone

There are no specific restrictions on food, beverages, or activities during treatment with Copaxone. Follow any special instructions given by your doctor.

Possible side effects of Copaxone

Stop using Copaxone and seek emergency medical attention or contact your doctor immediately if you experience an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; chest pain; hives; skin rash with irritation; dizziness; sweating; or severe pain at the injection site).

Other less serious side effects may be more likely to occur. Notify your doctor if you experience
- flushing, increased heart rate, or anxiety shortly following an injection;
- fever or chills;
- headache;
- weakness or joint pain;
- swelling or fluid retention;
- redness, pain, inflammation, itching, or a lump at the injection site;
- nausea, vomiting, or decreased appetite; or
- diarrhea.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect Copaxone

It is not known if other drugs interact with Copaxone. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products.

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abilify accupril accutane acetaminophen aciphex actifed actonel actos acyclovir adalat adderall adipex advair advil albuterol alesse aleve allegra allopurinol amaryl ambien amiodarone amitriptyline amoxicillin amoxil amphetamine anacin aprazolam aricept asacol aspirin atenolol ativan atorvastatin atrovent augmentin avandia avapro avastin avelox azmacort
B
baclofen
bactrim bactroban baycol benadryl bextra biaxin boniva bontril buspar buspirone
C
caduet campral camptosar capoten captopril cardizem cardura carisoprodol casodex catapress cefzil celebrex celexa cellcept cephalexin cialis cipro ciprodex clarinex claritin climara clindamycin clonazepam clonidine codeine codeprex combivent combivir concerta copaxone coreg coricidin cotrim coumadin cozaar crestor cubicin cyclobenzaprine cymbalta
D
darvocet demerol depakote desogen detrol dextromethorphan diazepam diclofenac didrex diflucan digoxin dilantin diltiazem dimetapp diovan diprivan ditropan doxazosin doxycycline drixoral duragesic dyazide
E
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F
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G
gabapentin gamimune gemfibrozil gemzar glipizide glucophage glucotrol glucovance glyburide glyburide guaifenesin guaifenex 
H
herceptin humalog humira hydroxyzine hyzaar  
I
ibuprofen imdur imitrex imodium inderal insulin integrilin iressa 
K
kaletra keflex kenalog keppra ketek klonopin kytril  
L
lamictal lamisil lanoxin lantus lasix lescol levaquin levitra levothyroxine levoxyl lexapro lidoderm lipitor lisinopril lithium lorazepam lortab lotensin lotrel lotrisone lovenox lupron luveris  
M
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N
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O
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P
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R
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S
sanctura seasonale sensipar serevent seroquel serzone singulair skelaxin soma somavert sonata spiriva spironolactone strattera striant sustiva synagis synthroid 
T
tamoxifen tavist taxol taxotere tegretol temazepam tenormin tenuate tequin terazosin tetracycline tiazac tindamax titralac tobradex topamax toprol tramadol trazodone triamcinolone triaminic triamterene tricor trileptal trimox triphasil trizivir truvada tylenol 
U
ultane ultracet ultram uroxatral
V
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W
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X
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Y
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Z
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