Darvocet

What is Darvocet

Propoxyphene (related to codeine) is in a class of drugs called narcotic analgesics. It works by changing the way the body feels pain.

Acetaminophen is a less potent pain reliever that increases the effects of propoxyphene.

Together, acetaminophen and propoxyphene are used to relieve pain.

Darvocet may also be used for purposes other than those listed in this medication guide.

General medical information about Darvocet

Propoxyphene may be habit forming. Physical and/or psychological dependence can occur, and withdrawal effects are possible if the medication is stopped suddenly after prolonged or high-dose treatment. Do not stop taking Darvocet suddenly without first talking to your doctor if you have been taking it continuously for more than 5 to 7 days. Your doctor may want to gradually reduce the dose.

Do not take Darvocet if you suffer from depression or have suicidal thoughts.

Do not take more of this medication than is prescribed. If the pain is not being adequately treated, talk to your doctor.

Do not take other over-the-counter and prescription products that contain acetaminophen. Too much acetaminophen could be dangerous. Talk to your doctor or pharmacist before taking any over-the-counter preparations.

Avoid alcohol while taking Darvocet. Alcohol can increase drowsiness and dizziness caused by the medication which could be dangerous. Also, alcohol may increase the risk of liver problems when taking acetaminophen.

Drowsiness or dizziness caused by Darvocet may be increased by other drugs such as antidepressants, alcohol, antihistamines, sedatives (used to treat insomnia), other pain relievers, anxiety medicines, and muscle relaxants. Together, these medicines may cause dangerous sedation, possibly resulting in unconsciousness or death. Tell your doctor about all medicines that you are taking, and do not take any medicine without first talking to your doctor.

What you should find out before taking Darvocet

Do not take Darvocet if you suffer from depression or have suicidal thoughts.

Before taking this medication, tell your doctor if you have:
- a history of drug or alcohol addiction;
- drink 3 or more alcoholic beverages per day;
- kidney disease;
- liver disease;
- asthma;
- urinary retention;
- an enlarged prostate;
- hypothyroidism;
- seizures or epilepsy;
- gallbladder disease;
- a head injury; or
- Addison's disease.

You may not be able to take Darvocet, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.

Propoxyphene may cause addiction and withdrawal symptoms as well as other harmful effects in an unborn baby. Do not take Darvocet without first talking to your doctor if you are pregnant or could become pregnant during treatment.

Propoxyphene may cause addiction and withdrawal symptoms in a nursing baby. Do not take Darvocet without first talking to your doctor if you are breast-feeding a baby.

If you are younger than 18 years of age or older than 60 years of age, you may be more likely to experience side effects from Darvocet therapy. Your doctor may prescribe a lower dose.

How should take Darvocet

Take Darvocet exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water.

Take Darvocet with food or milk if it upsets your stomach.

Do not take more of this medication than is prescribed. If the pain is not being adequately treated, talk to your doctor.

Constipation may be a side effect of treatment with Darvocet. Increasing the amount of fiber and water (six to eight full glasses) in the diet may reduce constipation.

Do not share this medication with anyone else.

Store Darvocet at room temperature away from moisture and heat.

If you miss a dose:

Take the missed dose as soon as you remember. Do not take a double dose of this medication. Wait the prescribed amount of time before taking your next dose.

What happens if you overdose:

Seek emergency medical attention if an overdose is suspected.

Symptoms of a Darvocet overdose include slow breathing, seizures, dizziness, weakness, loss of consciousness, coma, confusion, tiredness, cold and clammy skin, small pupils, nausea, vomiting, and sweating.

Avoid while taking Darvocet

Use caution when driving, operating machinery, or performing other hazardous activities. Darvocet may cause drowsiness. If you experience drowsiness, avoid these activities.

Possible side effects of Darvocet

If you experience any of the following serious side effects, stop taking Darvocet and seek emergency medical attention:
- an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
- slow, weak breathing;
- seizures;
- cold, clammy skin;
- severe weakness or dizziness;
- unconsciousness;
- yellowing of the skin or eyes; or
- unusual fatigue, bleeding, or bruising.

Other, less serious side effects may be more likely to occur. Continue to take Darvocet and talk to your doctor if you experience
- constipation;
- dry mouth, nausea, vomiting, or decreased appetite;
- dizziness, tiredness, or lightheadedness;
- muscle twitches;
- sweating;
- itching;
- decreased urination; or
- decreased sex drive.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect Darvocet

Do not take Darvocet if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days. Dangerous side effects could result.

Propoxyphene may increase the effects of oral anticoagulants such as warfarin (Coumadin) which could lead to bleeding. It may also increase the effects of carbamazepine (Tegretol) leading to toxicity. Be sure your doctor is aware if you are taking either of these medications.

Drugs other than those listed here may also interact with Darvocet. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.