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Emend

What is Emend

Emend blocks the actions of chemicals in the body that may cause nausea and vomiting.

Emend is used to prevent nausea and vomiting associated with cancer chemotherapy.

Emend may also be used for purposes other than those listed in this medication guide.

General medical information about Emend

Emend may decrease the effects of birth control pills, resulting in decreased protection from unintended pregnancy. Talk to your doctor about the use of other forms of birth control during treatment with Emend.

What should I discuss with my health care provider before taking Emend

Do not take Emend without first talking to your doctor if you are taking any of the following drugs:
- cisapride (Propulsid); or
- pimozide (Orap).

Emend may have a harmful interaction with either of the drugs listed above.

Before taking Emend, tell your doctor if you have liver problems or other medical problems. You may not be able to take Emend, or you may require a dosage adjustment or special monitoring during treatment.

Emend is in the FDA pregnancy category B. This means that Emend is not expected to be harmful to an unborn baby. Do not take Emend without first talking to your doctor if you are pregnant or could become pregnant during treatment.

It is not known whether Emend passes into breast milk. Do not take Emend without first talking to your doctor if you are breast-feeding a baby.

How should take Emend

Take Emend exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each oral dose with a full glass of water.

Emend can be taken with or without food.

The first dose of Emend is usually taken 1 hour before treatment with chemotherapy. Follow your doctor's instructions.

Store Emend at room temperature away from moisture and heat.

If you miss a dose:

Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication.

What happens if you overdose:

Seek emergency medical attention if an overdose is suspected.

Symptoms of an Emend overdose are not well known but might include drowsiness and headache.

Avoid while taking Emend

There are no restrictions on foods, beverages, or activities during treatment with Emend unless otherwise directed by your doctor.

Possible side effects of Emend

If you experience a rare but serious allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives) to Emend, stop taking the medication and seek emergency medical attention.

Other, less serious side effects may be more likely to occur. Continue to take the Emend and talk to your doctor if you experience
- fatigue or drowsiness;
- weakness;
- dizziness;
- constipation;
- diarrhea;
- nausea, stomach upset, or decreased appetite; or
- hiccups.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect Emend

Do not take Emend without first talking to your doctor if you are taking any of the following drugs:
- cisapride (Propulsid); or
- pimozide (Orap).

Emend may have a harmful interaction with either of the drugs listed above.

Before taking Emend, tell your doctor if you are taking warfarin (Coumadin). You may require a dosage adjustment or special monitoring during treatment.

Emend may decrease the effects of birth control pills, resulting in decreased protection from unintended pregnancy. Talk to your doctor about the use of other forms of birth control during treatment with Emend.

Emend may interact with many other medications. Do not take any other prescription or over-the-counter medicines, including herbal products, during treatment with Emend without first talking to your doctor.

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