|
What is Endocet
 Oxycodone
(related to codeine) is in a class of drugs called narcotic
analgesics. It relieves pain.
Acetaminophen
is a less potent pain reliever that increases the effects
of oxycodone.
Together,
acetaminophen and oxycodone are used to relieve moderate-to-severe
pain.
Endocet
may also be used for purposes other than those listed in this
medication guide.
General medical information about Endocet
Do not stop taking Endocet suddenly if you have been
taking it continuously for more than 5 to 7 days. Stopping
suddenly could cause withdrawal symptoms and make you feel
uncomfortable. Your doctor may want to gradually reduce
your dose.
Use caution when driving, operating machinery,
or performing other hazardous activities. Oxycodone may
cause drowsiness or dizziness. If you experience drowsiness
or dizziness, avoid these activities.
Avoid alcohol
while taking Endocet. Alcohol may increase the drowsiness
and dizziness caused by Endocet and could be dangerous.
Also, acetaminophen can be toxic to your liver when taken
with as little as 2 drinks of alcohol.
Also avoid
sleeping pills, tranquilizers, sedatives, and antihistamines
except under the supervision of your doctor. These medications
also may cause dangerous sedation.
Endocet may cause
constipation. Drink plenty of water (six to eight full glasses
a day) to lessen this side effect. Increasing the amount
of fiber in your diet can also help to alleviate constipation.
Never take more Endocet than is prescribed for you.
If your pain is not being adequately treated, talk to your
doctor.
Watch the acetaminophen content of other
over-the-counter and prescription products while taking
this medication. Do not take more than a total of 4 grams
(4000 mg) of acetaminophen per day.
Who should not take Endocet
Before taking Endocet, tell your doctor if you have:
- kidney disease;
- liver disease;
-
asthma;
- urinary retention;
- an enlarged
prostate;
- hypothyroidism;
- seizures or
epilepsy;
- gallbladder disease;
- a head
injury;
- Addison's disease; or
- a history
of alcohol or drug addiction.
You may not be able
to take Endocet, or you may require a dosage adjustment
or special monitoring during treatment if you have any of
the conditions listed above.
This drug combination
is in the FDA pregnancy category C. This means that it is
not known whether it will harm an unborn baby. Do not take
this medication without first talking to your doctor if
you are pregnant.
It is not known whether this drug
combination passes into breast milk. Do not take Endocet
without first talking to your doctor if you are breast-feeding
a baby.
If you are younger than 18 years of age or
older than 60 years of age, you may be more likely to experience
side effects from Endocet therapy. Use extra caution.
How should take Endocet Take Endocet exactly as directed by your doctor.
If you do not understand these directions, ask your pharmacist,
nurse, or doctor to explain them to you.
Take each
dose with a full glass of water.
Take Endocet with
food or milk if it upsets your stomach.
Never take
more Endocet than is prescribed for you. Too much Endocet
could be very harmful.
To ensure that you get a correct
dose, measure the liquid form of oxycodone with a special
dose-measuring spoon or cup, not with a regular table spoon.
If you do not have a dose-measuring device, ask your pharmacist
where you can get one.
Do not stop taking Endocet
suddenly if you have been taking it continuously for more
than 5 to 7 days. Stopping suddenly could cause withdrawal
symptoms and make you feel uncomfortable. Your doctor may
want to gradually reduce your dose.
Endocet may cause
constipation. Drink plenty of water (six to eight full glasses
a day) to lessen this side effect. Increasing the amount
of fiber in your diet can also help to alleviate constipation.
Do not share this medication with anyone else.
Store Endocet at room temperature away from moisture and
heat.
If you miss a dose: Take the missed dose as soon as you remember. Do
not take a double dose of this medication. Wait the prescribed
amount of time before taking your next dose.
What happens if you overdose: Seek emergency medical attention.
Symptoms
of an Endocet overdose include slow breathing, seizures,
dizziness, weakness, loss of consciousness, coma, confusion,
tiredness, cold and clammy skin, small pupils, nausea, vomiting,
and sweating.
Avoid while taking Endocet Use caution when driving, operating machinery, or
performing other hazardous activities. Oxycodone may cause
drowsiness or dizziness. If you experience drowsiness or
dizziness, avoid these activities.
Avoid alcohol
while taking Endocet. Alcohol may increase the drowsiness
and dizziness caused by Endocet and could be dangerous.
Also, acetaminophen can be toxic to your liver when taken
with as little as 2 drinks of alcohol.
Also avoid
sleeping pills, tranquilizers, sedatives, and antihistamines
except under the supervision of your doctor. These medications
also may cause dangerous sedation.
Watch the acetaminophen
content of other over-the-counter and prescription products
while taking this medication. Do not take more than a total
of 4 grams (4000 mg) of acetaminophen per day.
Possible side effects of Endocet If you experience any of the following serious side
effects, stop taking Endocet and seek emergency medical
attention or notify your doctor immediately:
- an
allergic reaction (difficulty breathing; closing of your
throat; swelling of your lips, tongue, or face; or hives);
- slow, weak breathing;
- seizures;
-
cold, clammy skin;
- severe weakness or dizziness;
- unconsciousness;
- yellowing of the skin
or eyes; or
- unusual fatigue, bleeding, or bruising.
Other, less serious side effects may be more likely
to occur. Continue to take Endocet and talk to your doctor
if you experience
- constipation;
- dry mouth,
nausea, vomiting, or decreased appetite;
- dizziness,
tiredness, or lightheadedness;
- muscle twitches;
- sweating;
- itching;
- decreased
urination; or
- decreased sex drive.
Endocet
is habit forming. Do not stop taking it suddenly.
Side effects other than those listed here may also occur.
Talk to your doctor about any side effect that seems unusual
or that is especially bothersome.
What other drugs will affect Endocet Do not take Endocet if you have taken a monoamine
oxidase inhibitor (MAOI) such as isocarboxazid (Marplan),
phenelzine (Nardil), or tranylcypromine (Parnate) in the
last 14 days. Dangerous side effects could result.
The most serious interactions affecting Endocet are with
those drugs that also cause sedation. The following drugs
may lead to dangerous sedation if taken with Endocet:
-
antihistamines such as brompheniramine (Dimetane, Bromfed,
others), diphenhydramine (Benadryl, Nytol, Compoz, others),
chlorpheniramine (Chlor-Trimeton, Teldrin, others), and
others;
- tricyclic antidepressants, such as amitriptyline
(Elavil) and doxepin (Sinequan), and serotonin reuptake
inhibitors such as fluoxetine (Prozac), sertraline (Zoloft),
and paroxetine (Paxil);
- other commonly used antidepressants,
including amoxapine (Asendin), clomipramine (Anafranil),
desipramine (Norpramin), imipramine (Tofranil), nortriptyline
(Pamelor), and protriptyline (Vivactil);
- anticholinergics
such as belladonna (Donnatal), clidinium (Quarzan), dicyclomine
(Bentyl, Antispas), hyoscyamine (Levsin, Anaspaz), ipratropium
(Atrovent), propantheline (Pro-Banthine), and scopolamine
(Transderm-Scop);
- phenothiazines such as chlorpromazine
(Thorazine), fluphenazine (Prolixin), thioridazine (Mellaril),
and prochlorperazine (Compazine); and
- tranquilizers
and sedatives such as phenobarbital (Solfoton, Luminal),
amobarbital (Amytal), secobarbital (Seconal), alprazolam
(Xanax), diazepam (Valium), lorazepam (Ativan), flurazepam
(ProSom), and temazepam (Restoril).
You may not be
able to take Endocet or you may require a dosage adjustment
or special monitoring during treatment if you are taking
any of the medicines listed above.
Watch the acetaminophen
content of other over-the-counter and prescription products
while taking this medication. Do not take more than a total
of 4 grams (4000 mg) of acetaminophen per day.
Drugs
other than those listed here may also interact with Endocet.
Talk to your doctor and pharmacist before taking any prescription
or over-the-counter medicines. |
