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Humira

What is Humira

Humira reduces the effects of a substance in the body called tumor necrosis factor alpha (TNF-alpha). TNF-alpha is involved in inflammatory processes in the body.

Humira is used in the treatment of rheumatoid arthritis.

Humira may also be used for purposes other than those listed here.

General medical information about Humira

Serious, even fatal, infections have been reported to occur during treatment with Humira. Contact your doctor immediately if you develop signs of infection such as fever or chills, sore throat, coughing, congestion, weight loss, night sweats, or other signs of infection; redness, pain, or swelling of a skin wound; or burning or difficult urination.

A tuberculin skin test should be performed before starting treatment with Humira. Latent (inactive) tuberculosis infection may become symptomatic due to treatment with Humira.

Treatment with an immunosuppressant such as Humira may increase the risk of developing certain types of cancer (e.g., lymphoma). Treatment with Humira may also increase the risk of developing an autoimmune disorder such as a lupus-like syndrome. Talk to your doctor about the risks and benefits of this medication.

What you should discuss with your doctor before using Humira

Before using Humira, tell your doctor if you
- have an active infection or a history of recurrent infections;
- have ever had tuberculosis (TB) or if you have been in close contact with someone who has had tuberculosis;
- have experienced numbness or tingling or have ever had a disease that affects the nervous system such as multiple sclerosis;
- are scheduled to have major surgery;
- are scheduled to receive any vaccinations; or
- have an allergy to latex or rubber (the needle covers on the pre-filled syringes contain latex).

You may not be able to use Humira, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.

Humira is in the FDA pregnancy category B. This means that it is not expected to be harmful to an unborn baby. Do not use Humira without first talking to your doctor if you are pregnant or could become pregnant during treatment.

It is not known whether Humira passes into breast milk. Do not use Humira without first talking to your doctor if you are breast-feeding a baby.

How should you use Humira

Use Humira exactly as directed by your doctor. If you do not understand these directions, ask your doctor, nurse, or pharmacist to explain them to you.

Humira is administered as a subcutaneous (under the skin) injection. Do not inject this medication intramuscularly (into a muscle) or intravenously (into a vein).

Your doctor or nurse will give you detailed instructions on how to inject Humira. It can be injected into the abdomen (avoid the area 2 inches around the navel) or front of the thighs. Rotate the injection sites as directed by your doctor. Each new injection should be given at least one inch from the site you used before.

Do not inject the medication into areas

Where the skin is tender, bruised, red, or hard or

Where you have scars or stretch marks.

Do not shake the vials or pre-filled syringes of Humira.

Inspect the vial or pre-filled syringe of Humira before injection. The liquid should be clear and colorless. Do not use the medication if it is cloudy or discolored, or if it has flakes or particles in it.

Each vial or pre-filled syringe of Humira is intended for one use only. Throw away any unused portion of the medication. Do not save it for later use, it does not contain a preservative.

A tuberculin skin test should be performed before starting treatment with Humira. Latent (inactive) tuberculosis infection may become symptomatic due to treatment with Humira.

It is important to use Humira regularly to get the most benefit.

Dispose of all needles and syringes in an appropriate puncture resistant container.

Store Humira in the refrigerator (36 to 46 degrees Fahrenheit or 2 to 8 degrees Celsius) in the original container until it is used. Do not allow the product to freeze and do not use it beyond the expiration date. If the medication needs to be transported during travel, store it in a cool carrier with an ice pack and protect it from light.

If you miss a dose:

If you miss a dose of Humira, inject the dose as soon as you remember. Then, inject the next dose when the next scheduled dose is due. Do not use a double dose of the medication.

What happens if you overdose:

Contact your doctor if an overdose of Humira is suspected. An overdose of Humira is unlikely to be harmful.

What should you avoid while using Humira

Humira can lower the activity of the immune system making you susceptible to infections. Avoid contact with people who have colds, the flu, or other contagious illnesses and do not receive "live" vaccines during treatment with Humira without first talking to your doctor. In addition, avoid contact with individuals who have recently been vaccinated with a live vaccine. There is a chance that the virus can be passed on to you. Contact your doctor immediately if you develop signs of infection.

Possible side effects of Humira

Serious, even fatal, infections have been reported to occur during treatment with Humira. Contact your doctor immediately if you develop signs of infection such as fever or chills, sore throat, coughing, congestion, weight loss, night sweats, or other signs of infection; redness, pain, or swelling of a skin wound; or burning or difficult urination.

Treatment with an immunosuppressant such as Humira may increase the risk of developing certain types of cancer (e.g., lymphoma). Treatment with Humira may also increase the risk of developing an autoimmune disorder such as a lupus-like syndrome. Talk to your doctor about the risks and benefits of this medication.

If you experience any of the following serious side effects, stop using Humira and seek emergency medical attention or contact your doctor immediately:
- an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
- numbness, tingling, or weakness;
- problems with vision;
- dizziness;
- chest pain or shortness of breath; or
- skin rash on the arms or cheeks that is sensitive to the sun.

Other less serious side effects may be more likely to occur. Contact your doctor if you develop
- headache;
- nausea; or
- redness, rash, swelling, itching, or bruising where the injection was given.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect Humira

Do not receive "live" vaccinations during treatment with Humira. Administration of a live vaccine may cause an infection or be ineffective during treatment with Humira.

Other medications may interact with Humira or affect your condition. Talk to your doctor or pharmacist before taking other prescription or over-the-counter medications, including herbal products, during treatment with Humira.

All prescription drugs:

A
abilify accupril accutane acetaminophen aciphex actifed actonel actos acyclovir adalat adderall adipex advair advil albuterol alesse aleve allegra allopurinol amaryl ambien amiodarone amitriptyline amoxicillin amoxil amphetamine anacin aprazolam aricept asacol aspirin atenolol ativan atorvastatin atrovent augmentin avandia avapro avastin avelox azmacort
B
baclofen
bactrim bactroban baycol benadryl bextra biaxin boniva bontril buspar buspirone
C
caduet campral camptosar capoten captopril cardizem cardura carisoprodol casodex catapress cefzil celebrex celexa cellcept cephalexin cialis cipro ciprodex clarinex claritin climara clindamycin clonazepam clonidine codeine codeprex combivent combivir concerta copaxone coreg coricidin cotrim coumadin cozaar crestor cubicin cyclobenzaprine cymbalta
D
darvocet demerol depakote desogen detrol dextromethorphan diazepam diclofenac didrex diflucan digoxin dilantin diltiazem dimetapp diovan diprivan ditropan doxazosin doxycycline drixoral duragesic dyazide
E
effexor elavil elocon eloxatin emend enalapril enbrel endocet engerix-b entex epogen epzicom erbitux ertaczo ery-tab erythromycin estradiol evista 
F
fabrazyme famotidine fazaclo fenofibrate fioricet fiorinal flexeril flomax flonase flovent fluoxetine fosamax fosrenol furosemide  
G
gabapentin gamimune gemfibrozil gemzar glipizide glucophage glucotrol glucovance glyburide glyburide guaifenesin guaifenex 
H
herceptin humalog humira hydroxyzine hyzaar  
I
ibuprofen imdur imitrex imodium inderal insulin integrilin iressa 
K
kaletra keflex kenalog keppra ketek klonopin kytril  
L
lamictal lamisil lanoxin lantus lasix lescol levaquin levitra levothyroxine levoxyl lexapro lidoderm lipitor lisinopril lithium lorazepam lortab lotensin lotrel lotrisone lovenox lupron luveris  
M
macrobid magnevist meclizine medroxyprogesterone meridia metformin methadone methamphetamine methotrexate methylphenidate methylprednisolone metoclopramide metoprolol metronidazole miacalcin minocycline mobic monopril morphine motrin myfortic  
N
naproxen nasacort nasonex natrecor neulasta neupogen neurontin nexium nifedipine nitrofurantoin norco nortriptyline norvasc  
O
omeprazole omnicef orthovisc oxybutynin oxycodone oxycontin oxytrol  
P
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R
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S
sanctura seasonale sensipar serevent seroquel serzone singulair skelaxin soma somavert sonata spiriva spironolactone strattera striant sustiva synagis synthroid 
T
tamoxifen tavist taxol taxotere tegretol temazepam tenormin tenuate tequin terazosin tetracycline tiazac tindamax titralac tobradex topamax toprol tramadol trazodone triamcinolone triaminic triamterene tricor trileptal trimox triphasil trizivir truvada tylenol 
U
ultane ultracet ultram uroxatral
V
valium valtrex vaniqa vasotec velcade verapamil viagra vicodin vicoprofen vidaza viracept viread vytorin  
W
warfarin wellbutrin  
X
xalatan xanax xenical xifaxan xolair xopenex xyrem  
Y
yasmin 
Z
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