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Hyzaar

What is Hyzaar

Losartan is in a class of drugs called angiotensin II receptor antagonists.

Hydrochlorothiazide is a thiazide diuretic (water pill). It increases the amount of water and salt you lose in your urine. Hydrochlorothiazide is used to lower blood pressure and to decrease edema (swelling).

Hyzaar is used to reduce hypertension (high blood pressure).

Hyzaar may also be used for purposes other than those listed in this medication guide.

General medical information about Hyzaar

Do not take Hyzaar if you are pregnant or planning a pregnancy. When used during the second and third trimesters of pregnancy, losartan can cause injury and even death to the developing fetus. Notify your doctor immediately if you think you might be pregnant.

Use caution when driving, operating machinery, or performing other hazardous activities. Hyzaar may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities. Also use caution when rising from a sitting or lying position.

Use alcohol cautiously. Alcohol may further lower blood pressure and increase drowsiness and dizziness while you are taking Hyzaar.

Who should not take Hyzaar

Do not take Hyzaar without first talking to your doctor if you have an allergy to sulfa-based drugs such as sulfa antibiotics. You may have an allergic reaction to hydrochlorothiazide.

Before taking Hyzaar, tell your doctor if you
- have diabetes;
- have gout;
- have a collagen vascular disease such as systemic lupus erythematosus;
- have pancreatitis;
- have kidney disease;
- have liver disease;
- have any type of heart disease or have had a stroke;
- are on a salt-restricted diet or have high levels of potassium in your blood; or
- are taking potassium supplements (e.g., K-Dur, Klor-Con, others), or a potassium-sparing diuretic such as amiloride (Midamor), triamterene (Dyrenium, Dyazide, Maxzide), or spironolactone (Aldactone).

You may not be able to take Hyzaar, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.

Hyzaar is in the FDA pregnancy category D. This means that it is known to harm an unborn baby. When used during the second and third trimesters of pregnancy, losartan can cause injury and even death of the developing fetus. Do not take this medication if you are pregnant.

It is not known whether this drug passes into breast milk. Do not take Hyzaar without first talking to your doctor if you are breast-feeding a baby.

How should take Hyzaar

Take Hyzaar exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass (8 ounces) of water.

You can take Hyzaar with or without food.

Do not stop taking this medication without first talking to your doctor. If you stop taking this medication, your condition could become worse.

Call your doctor before taking any more doses if you develop severe dizziness or fainting.

Store Hyzaar at room temperature away from moisture and heat.

If you miss a dose:

Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of this medication.

What happens if you overdose:

Seek emergency medical attention.

Symptoms of a Hyzaar overdose are not well known but may include dizziness, weakness, fainting, and fatigue.

Avoid while taking Hyzaar

Use caution when driving, operating machinery, or performing other hazardous activities. Hyzaar may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities. Also use caution when rising from a sitting or lying position.

Use alcohol cautiously. Alcohol may further lower blood pressure and increase drowsiness and dizziness while you are taking Hyzaar.

Avoid a diet high in salt. Too much salt may cause your body to retain water and may decrease the effects of hydrochlorothiazide.

Do not use salt substitutes or take potassium supplements without first talking to your doctor. Losartan can affect potassium levels in your body.

Avoid prolonged exposure to sunlight. Hyzaar may increase the sensitivity of your skin to sunlight. Use a sunscreen and wear protective clothing when exposure to the sun is unavoidable.

Avoid becoming overheated in hot weather. It is easy to become dangerously dehydrated while taking hydrochlorothiazide.

Possible side effects of Hyzaar

If you experience any of the following serious side effects, stop taking Hyzaar and call your doctor immediately or seek emergency medical treatment.
- an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);
- little or no urine;
- unusual fatigue, abnormal bleeding or bruising;
- yellow skin or eyes, confusion; or
- fainting.

Other, less serious side effects may be more likely to occur. Continue to take Hyzaar and talk to your doctor if you experience
- diarrhea or upset stomach;
- muscle pain or cramps;
- dizziness;
- insomnia;
- congestion or cough;
- tingling or numbness in your arms, legs, hands, or feet;
- excessive urination;
- muscle weakness or cramps;
- increased hunger or thirst;
- nausea or decreased appetite; or
- sensitivity to sunlight.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect Hyzaar

Before taking Hyzaar, tell your doctor if you are taking
- a potassium supplement such as K-Dur, Klor-Con, and others;
- a potassium-sparing diuretic (water pill) such as amiloride (Midamor), spironolactone (Aldactone), or triamterene (Dyrenium, Dyazide, Maxzide);
- a barbiturate such as phenobarbital (Luminal, Solfoton), pentobarbital (Nembutal), secobarbital (Seconal), mephobarbital (Mebaral), and others;
- a nonsteroidal anti-inflammatory drug (NSAID) such as ibuprofen (Motrin, Advil, Nuprin), ketoprofen (Orudis, Orudis KT, Oruvail), diclofenac (Cataflam, Voltaren), indomethacin (Indocin), nabumetone (Relafen), oxaprozin (Daypro), naproxen (Naprosyn, Anaprox, Aleve), and others;
- an oral diabetes medication such as glipizide (Glucotrol), glyburide (Micronase, Glynase, Diabeta), chlorpropamide (Diabinese), tolazamide (Tolinase), or tolbutamide (Orinase);
- cholestyramine (Questran) or colestipol (Colestid);
- lithium (Lithobid, Eskalith, others); or
- digoxin (Lanoxin).

You may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above.

Drugs other than those listed here may also interact with Hyzaar or affect your condition. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

All prescription drugs:

A
abilify accupril accutane acetaminophen aciphex actifed actonel actos acyclovir adalat adderall adipex advair advil albuterol alesse aleve allegra allopurinol amaryl ambien amiodarone amitriptyline amoxicillin amoxil amphetamine anacin aprazolam aricept asacol aspirin atenolol ativan atorvastatin atrovent augmentin avandia avapro avastin avelox azmacort
B
baclofen
bactrim bactroban baycol benadryl bextra biaxin boniva bontril buspar buspirone
C
caduet campral camptosar capoten captopril cardizem cardura carisoprodol casodex catapress cefzil celebrex celexa cellcept cephalexin cialis cipro ciprodex clarinex claritin climara clindamycin clonazepam clonidine codeine codeprex combivent combivir concerta copaxone coreg coricidin cotrim coumadin cozaar crestor cubicin cyclobenzaprine cymbalta
D
darvocet demerol depakote desogen detrol dextromethorphan diazepam diclofenac didrex diflucan digoxin dilantin diltiazem dimetapp diovan diprivan ditropan doxazosin doxycycline drixoral duragesic dyazide
E
effexor elavil elocon eloxatin emend enalapril enbrel endocet engerix-b entex epogen epzicom erbitux ertaczo ery-tab erythromycin estradiol evista 
F
fabrazyme famotidine fazaclo fenofibrate fioricet fiorinal flexeril flomax flonase flovent fluoxetine fosamax fosrenol furosemide  
G
gabapentin gamimune gemfibrozil gemzar glipizide glucophage glucotrol glucovance glyburide glyburide guaifenesin guaifenex 
H
herceptin humalog humira hydroxyzine hyzaar  
I
ibuprofen imdur imitrex imodium inderal insulin integrilin iressa 
K
kaletra keflex kenalog keppra ketek klonopin kytril  
L
lamictal lamisil lanoxin lantus lasix lescol levaquin levitra levothyroxine levoxyl lexapro lidoderm lipitor lisinopril lithium lorazepam lortab lotensin lotrel lotrisone lovenox lupron luveris  
M
macrobid magnevist meclizine medroxyprogesterone meridia metformin methadone methamphetamine methotrexate methylphenidate methylprednisolone metoclopramide metoprolol metronidazole miacalcin minocycline mobic monopril morphine motrin myfortic  
N
naproxen nasacort nasonex natrecor neulasta neupogen neurontin nexium nifedipine nitrofurantoin norco nortriptyline norvasc  
O
omeprazole omnicef orthovisc oxybutynin oxycodone oxycontin oxytrol  
P
paraplatin patanol paxil pegasys penicillin pepcid percocet percodan percogesic phendimetrazine phenergan phentermine phenytoin plavix plendil potassium pravachol prednisone premarin prempro prevacid prilosec prinivil procrit promethazine propecia propofol propoxyphene propranolol protonix proventil provigil prozac pseudoephedrine pulmicort  
R
ranitidine rebetol reglan relafen relpax remeron remicade renagel renova rhinocort riomet risperdal risperidone ritalin rituxan rocephin rogaine roxicet  
S
sanctura seasonale sensipar serevent seroquel serzone singulair skelaxin soma somavert sonata spiriva spironolactone strattera striant sustiva synagis synthroid 
T
tamoxifen tavist taxol taxotere tegretol temazepam tenormin tenuate tequin terazosin tetracycline tiazac tindamax titralac tobradex topamax toprol tramadol trazodone triamcinolone triaminic triamterene tricor trileptal trimox triphasil trizivir truvada tylenol 
U
ultane ultracet ultram uroxatral
V
valium valtrex vaniqa vasotec velcade verapamil viagra vicodin vicoprofen vidaza viracept viread vytorin  
W
warfarin wellbutrin  
X
xalatan xanax xenical xifaxan xolair xopenex xyrem  
Y
yasmin 
Z
zanaflex zantac zavesca zelnorm zemplar zerit zestoretic zestril zetia ziac zithromax zocor zofran zoladex zoloft zometa zorbtive zosyn zovirax zyrtec zyvox