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Lescol

What is Lescol

Lescol blocks the production of cholesterol (a type of fat) in the body.

Lescol is used to reduce the amounts of LDL (bad) cholesterol and total cholesterol in your blood. Lescol also reduces the amounts of triglycerides (another type of fat) and apolipoprotein B (a protein needed to make cholesterol) in your blood. These actions are important in reducing the risk of hardening of the arteries, which can lead to heart attacks, stroke, and peripheral vascular disease.

Lescol may also be used for purposes other than those listed in this medication guide.

General medical information about Lescol

Do not take Lescol without first talking to your doctor if you have liver disease.

Alcohol and Lescol can both damage your liver. Discuss with your doctor the amount of alcohol that you drink so that it can be determined if Lescol is the best choice for lowering your cholesterol.

Do not take Lescol if you are pregnant, if you are planning a pregnancy, or if you are breast-feeding a baby.

Contact your doctor immediately if you experience unexplained muscle pain, tenderness, or weakness, especially if it is accompanied by a fever, flulike symptoms, or yellowing of your skin or eyes.

 

Who should not take Lescol

Do not take Lescol without first talking to your doctor if you have liver disease.

Before taking Lescol, tell your doctor if you
- have kidney disease,
- drink alcoholic beverages,
- have a chronic muscular disease, or
- have a blood disorder.

You may not be able to take Lescol, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.

Lescol is in the FDA pregnancy category X. This means that Lescol will cause birth defects if it is taken during pregnancy. Cholesterol is very important for the proper development of a baby. Do not take Lescol if you are pregnant or if you are planning a pregnancy.

Lescol passes into breast milk and may harm a nursing infant. Do not take Lescol without first talking to your doctor if you are breast-feeding a baby.

Lescol has not been approved for use by children younger than 18 years of age.

How should take Lescol

Take Lescol exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water.

For the greatest effect, Lescol is usually taken at bedtime or with an evening meal. Lescol may also be taken twice daily. Follow your doctor's directions.

Do not crush, chew, or break the extended-release tablets (Lescol XL). Swallow them whole.

Your doctor will probably want to monitor your liver function with blood tests before starting treatment with Lescol and at twelve weeks after both the start of your treatment and any increase in dose. Depending on the results of these tests, your doctor can determine how much monitoring you will require.

Eat a low-fat, low-cholesterol diet. To realize beneficial effects from Lescol, avoid fatty, high-cholesterol foods.

Do not stop taking Lescol without first talking to your doctor. It may be weeks or months before beneficial effects are seen from Lescol.

Store Lescol at room temperature away from moisture and heat.

If you miss a dose:

Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of this medication.

What happens if you overdose:

Seek emergency medical attention.

Symptoms of a Lescol overdose include nausea, diarrhea, stomach distress, and indigestion.

Avoid while taking Lescol

Alcohol and Lescol can both damage your liver. Discuss with your doctor the amount of alcohol that you drink so that it can be determined if Lescol is the best choice for lowering your cholesterol.

Possible side effects of Lescol

If you experience any of the following serious side effects, stop taking Lescol and call your doctor immediately:
- an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);
- muscle aches, pain, or weakness;
- "flu-like" symptoms;
- decreased urine or rust-colored urine;
- blurred vision; or
- yellowing of your eyes or skin.

Other, less serious side effects may be more likely to occur. Continue to take Lescol and talk to your doctor if you experience
- gas, bloating, nausea, stomach upset, heartburn, abdominal pain, constipation, or diarrhea;
- cough;
- headache; or
- insomnia.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect Lescol

Do not take Lescol without first talking to your doctor if you are taking any of the following medicines:
- cyclosporine (Sandimmune, Neoral);
- gemfibrozil (Lopid);
- niacin (Nicolar, Nicobid, Nicotinex, others); or
- clarithromycin (Biaxin);
- erythromycin (E-Mycin, E.E.S., Ery-Tab, Ilotycin, Eryc, PCE, Ilosone, others).

These medications may interact with Lescol and damage your muscles.

Before taking Lescol, tell your doctor if you are taking any of the following medicines:
- other cholesterol-lowering drugs such as cholestyramine (Questran) or colestipol (Colestid);
- digoxin (Lanoxin, Lanoxicaps); or
- warfarin (Coumadin).

You may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above.

Drugs other than those listed here may also interact with Lescol. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

All prescription drugs:

A
abilify accupril accutane acetaminophen aciphex actifed actonel actos acyclovir adalat adderall adipex advair advil albuterol alesse aleve allegra allopurinol amaryl ambien amiodarone amitriptyline amoxicillin amoxil amphetamine anacin aprazolam aricept asacol aspirin atenolol ativan atorvastatin atrovent augmentin avandia avapro avastin avelox azmacort
B
baclofen
bactrim bactroban baycol benadryl bextra biaxin boniva bontril buspar buspirone
C
caduet campral camptosar capoten captopril cardizem cardura carisoprodol casodex catapress cefzil celebrex celexa cellcept cephalexin cialis cipro ciprodex clarinex claritin climara clindamycin clonazepam clonidine codeine codeprex combivent combivir concerta copaxone coreg coricidin cotrim coumadin cozaar crestor cubicin cyclobenzaprine cymbalta
D
darvocet demerol depakote desogen detrol dextromethorphan diazepam diclofenac didrex diflucan digoxin dilantin diltiazem dimetapp diovan diprivan ditropan doxazosin doxycycline drixoral duragesic dyazide
E
effexor elavil elocon eloxatin emend enalapril enbrel endocet engerix-b entex epogen epzicom erbitux ertaczo ery-tab erythromycin estradiol evista 
F
fabrazyme famotidine fazaclo fenofibrate fioricet fiorinal flexeril flomax flonase flovent fluoxetine fosamax fosrenol furosemide  
G
gabapentin gamimune gemfibrozil gemzar glipizide glucophage glucotrol glucovance glyburide glyburide guaifenesin guaifenex 
H
herceptin humalog humira hydroxyzine hyzaar  
I
ibuprofen imdur imitrex imodium inderal insulin integrilin iressa 
K
kaletra keflex kenalog keppra ketek klonopin kytril  
L
lamictal lamisil lanoxin lantus lasix lescol levaquin levitra levothyroxine levoxyl lexapro lidoderm lipitor lisinopril lithium lorazepam lortab lotensin lotrel lotrisone lovenox lupron luveris  
M
macrobid magnevist meclizine medroxyprogesterone meridia metformin methadone methamphetamine methotrexate methylphenidate methylprednisolone metoclopramide metoprolol metronidazole miacalcin minocycline mobic monopril morphine motrin myfortic  
N
naproxen nasacort nasonex natrecor neulasta neupogen neurontin nexium nifedipine nitrofurantoin norco nortriptyline norvasc  
O
omeprazole omnicef orthovisc oxybutynin oxycodone oxycontin oxytrol  
P
paraplatin patanol paxil pegasys penicillin pepcid percocet percodan percogesic phendimetrazine phenergan phentermine phenytoin plavix plendil potassium pravachol prednisone premarin prempro prevacid prilosec prinivil procrit promethazine propecia propofol propoxyphene propranolol protonix proventil provigil prozac pseudoephedrine pulmicort  
R
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S
sanctura seasonale sensipar serevent seroquel serzone singulair skelaxin soma somavert sonata spiriva spironolactone strattera striant sustiva synagis synthroid 
T
tamoxifen tavist taxol taxotere tegretol temazepam tenormin tenuate tequin terazosin tetracycline tiazac tindamax titralac tobradex topamax toprol tramadol trazodone triamcinolone triaminic triamterene tricor trileptal trimox triphasil trizivir truvada tylenol 
U
ultane ultracet ultram uroxatral
V
valium valtrex vaniqa vasotec velcade verapamil viagra vicodin vicoprofen vidaza viracept viread vytorin  
W
warfarin wellbutrin  
X
xalatan xanax xenical xifaxan xolair xopenex xyrem  
Y
yasmin 
Z
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