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Myfortic

What is Myfortic

Myfortic is an immunosuppressant. Immunosuppressants decrease the actions of the body's immune system.

Myfortic is used to prevent the body from rejecting a kidney transplant. It is usually combined with cyclosporine (Sandimmune, Neoral) and a steroid medication.

Myfortic may also be used for purposes other than those listed in this medication guide.

General medical information about Myfortic

Treatment with Myfortic may increase your risk of infection and the development of lymphoma and other types of cancer. Notify your doctor immediately if you develop fever or chills, a sore throat, unusual bleeding or bruising, mouth sores, abdominal pain, pale stools, or darkened urine. These symptoms could be early signs of dangerous side effects.

Myfortic has caused birth defects in animals, and therefore is not recommended for use during pregnancy. Your doctor may ask that you have a pregnancy test with negative results within 1 week of starting therapy with Myfortic. Two reliable forms of birth control must be used simultaneously before starting treatment, during treatment, and for six weeks following treatment with Myfortic, unless abstinence is the chosen method or if you have had a hysterectomy. Do not take this medication without first talking to your doctor if you are pregnant or could become pregnant during treatment.

Do not crush, chew, or cut the tablets. The tablets have a special coating to protect the stomach from irritation.

Tell your doctor and dentist that you are taking this medication before having surgery, before starting any other medicines, and before receiving any vaccinations.

Myfortic may increase the risk of developing skin cancer. Limit exposure to sunlight and UV light by wearing protective clothing and using a sunscreen with a sun protection factor (SPF) rating of 15 or higher.

What you should find out before taking Myfortic

Before taking Myfortic, tell your doctor if you have:
- a stomach ulcer or other stomach disease;
- a viral, bacterial, or fungal infection; or
- a rare hereditary deficiency of hypoxanthine-guanine phosphoribosyl-transferase (HGPRT) such as Lesch-Nyhan and Kelley-Seegmiller syndrome.

You may not be able to take Myfortic, or you may require a dosage adjustment or special monitoring if you have any of the conditions listed above.

Myfortic has caused birth defects in animals, and therefore is not recommended for use during pregnancy. Your doctor may ask that you have a pregnancy test with negative results within 1 week of starting therapy with Myfortic. Two reliable forms of birth control must be used simultaneously before starting treatment, during treatment, and for six weeks following treatment with Myfortic, unless abstinence is the chosen method or if you have had a hysterectomy. Do not take this medication without first talking to your doctor if you are pregnant or could become pregnant during treatment.

It is not known whether Myfortic passes into breast milk. Do not take Myfortic without first talking to your doctor if you are breast-feeding a baby.

How should take Myfortic

Take Myfortic exactly as directed by your doctor. If you do not understand these directions, ask your doctor, nurse, or pharmacist to explain them to you.

Take each dose with a full glass of water.

Take Myfortic on an empty stomach, 1 hour before or 2 hours after a meal unless otherwise directed by your doctor.

Myfortic is usually taken twice a day. Follow your doctor's instructions.

Do not crush, chew, or cut the tablets. The tablets have a special coating to protect the stomach from irritation.

It is important to take Myfortic regularly to get the most benefit.

Your doctor may want you to have blood tests or other medical evaluations during treatment with Myfortic to monitor progress and side effects.

Store Myfortic at room temperature away from moisture and heat.

If you miss a dose:

Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the dose you missed, and take only the next regularly scheduled dose. Do not take a double dose of this medication unless otherwise directed by your doctor.

Notify your doctor if you miss a dose of this medication.

What happens if you overdose:

Seek emergency medical attention if an overdose is suspected.

Symptoms of a Myfortic overdose may include nausea, vomiting, diarrhea, and unusual bleeding or bruising.

Avoid while taking Myfortic

Avoid sources of infection. Myfortic decreases the body's immune system, and you are more susceptible to infection. Notify your doctor at the first sign of fever, chills, or a sore throat.

Do not receive "live" vaccines during treatment with Myfortic. Administration of a live vaccine may be dangerous during treatment with Myfortic.

Tell your doctor and dentist that you are taking this medication before having surgery, before starting any other medicines, and before receiving any vaccinations.

Myfortic may increase the risk of developing skin cancer. Limit exposure to sunlight and UV light by wearing protective clothing and using a sunscreen with a sun protection factor (SPF) rating of 15 or higher.

Possible side effects of Myfortic

Treatment with Myfortic may increase your risk of infection and the development of lymphoma and other types of cancer. Notify your doctor immediately if you develop fever or chills, a sore throat, unusual bleeding or bruising, mouth sores, abdominal pain, pale stools, or darkened urine. These symptoms could be early signs of dangerous side effects.

If you experience any of the following serious side effects, stop taking Myfortic and seek emergency medical attention or contact your doctor immediately:
- an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
- unusual tiredness or weakness;
- painful or difficult urination;
- black, bloody, or tarry stools or blood in vomit;
- severe nausea, vomiting, or diarrhea; or
- a sudden unusual feeling of discomfort or illness.

Other, less serious side effects may also occur. Continue to take Myfortic and notify your doctor if you experience
- upset stomach, nausea, or vomiting;
- diarrhea or constipation;
- mild weakness;
- tremor or dizziness;
- headache;
- insomnia;
- swelling of the feet or lower legs; or
- a skin rash.

Treatment with Myfortic increases the risk of cancer of the immune system.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect Myfortic

Before taking Myfortic, tell your doctor if you are taking any of the following medicines:
- another immunosuppressant medicine such as azathioprine (Imuran), tacrolimus (Prograf), or daclizumab (Zenapax);
- cholestyramine (Questran);
- an antacid (prescription or over-the-counter);
- acyclovir (Zovirax) or ganciclovir (Cytovene);
- probenecid (Benemid);
- phenytoin (Dilantin);
- theophylline (Theo-Dur, Theochron, Theolair, others);
- oral contraceptives; or
- any type of vaccination.

You may not be able to take Myfortic, or you may require a dosage adjustment or special monitoring if you are taking any of the medicines listed above.

Drugs other than those listed here may also interact with Myfortic. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

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