What is Neulasta
is a protein that stimulates production of white blood cells.
White blood cells are important for protecting the body from
is used to increase white blood cells and therefore decrease
the risk of infection in patients with non-myeloid (not bone
marrow) cancers while receiving cancer chemotherapy (drugs).
may also be used for purposes other than those listed in this
General medical information about Neulasta
Do not administer an injection if you are unsure
how to properly give the injection, how much to inject,
or how often to inject the medication. Call your doctor,
nurse, or pharmacist to go over the instructions with you.
Contact your doctor if you develop a fever; chills;
sore throat; congestion; or redness, pain, or swelling around
a wound or sore while using Neulasta. These may be signs
What you should discuss with your doctor before using
Do not use Neulasta if you have an allergy to the
bacterium E. coli or the drug filgrastim (Neupogen). You
may also have an allergic reaction to Neulasta.
using this medication, tell your doctor if you:
are undergoing radiation or chemotherapy;
sickle cell disease;
- have myeloid (bone marrow)
- have kidney disease; or
- have liver
You may not be able to uses Neulasta or
you may require a dosage adjustment or special monitoring
during treatment if you have any of the conditions listed
Neulasta is in the FDA pregnancy category
C. This means that it is not known whether Neulasta will
be harmful to an unborn baby. Do not use Neulasta without
first talking to your doctor if you are pregnant or could
become pregnant during treatment.
It is not known
whether Neulasta passes into breast milk. Do not use Neulasta
without first talking to your doctor if you are breast-feeding
How should you use Neulasta Use Neulasta exactly as directed by your doctor.
If you do not understand these instructions, ask your pharmacist,
nurse, or doctor to explain them to you.
is administered by subcutaneous (SC) injection. If you are
injecting the medication at home, your doctor, nurse, or
pharmacist will give you specific instructions on how and
Where it should be injected. Do not administer an injection
if you are unsure how to properly give the injection, how
much to inject, or how often to inject the medication. Call
your doctor, nurse, or pharmacist to go over the instructions
Neulasta is supplied in prefilled syringes,
each intended to administer a single dose.
shake the syringes containing Neulasta.
Do not inject
Neulasta that is discolored or that has particles in it.
Before injection, a prefilled syringe of Neulasta
may be allowed to reach room temperature for a maximum of
48 hours but should be protected from light. Neulasta left
at room temperature for more than 48 hours should be thrown
After injecting a dose of Neulasta, slide the
needle guard into place until the needle is completely covered
and the guard clicks into place. Throw away the syringe,
with the needle guard in place, in a puncture resistant
Your doctor will want you to have periodic
blood tests during treatment with Neulasta to monitor effectiveness
and possible side effects of the medication.
Neulasta prefilled syringes in the refrigerator between
2 and 8 degrees Celsius (36 to 46 degrees Fahrenheit) in
the original carton to protect from light. Do not allow
the medication to freeze. If a vial of medication is accidentally
frozen, it can be thawed in the refrigerator and used at
a later time. If the vial is frozen a second time, do not
use it at all. Discard all unused medication on the expiration
If you miss a dose: Contact your doctor if you miss a dose of Neulasta.
What happens if you overdose: Seek emergency medical attention if an overdose is
Symptoms of a Neulasta overdose are not
What should you avoid while using Neulasta There are no restrictions regarding foods, beverages,
or activities during treatment with Neulasta unless your
doctor directs otherwise.
Possible side effects of Neulasta If you experience any of the following serious side
effects, seek emergency medical treatment or contact your
- an allergic reaction (difficulty
breathing; closing of the throat; swelling of the lips,
tongue, or face; or hives);
- fever or chills;
sore throat or congestion;
- redness, pain, or swelling
around a wound or sore;
- difficulty breathing or
shortness of breath; or
- left upper stomach or shoulder
Other, less serious side effects may be more
likely to occur. Continue to use Neulasta and talk to your
doctor if you experience:
- muscle, joint, or bone
- sores in the mouth or throat;
- nausea, vomiting, diarrhea, or constipation.
Side effects other than those listed here may also
occur. Talk to your doctor about any side effect that seems
unusual or that is especially bothersome.
What other drugs will affect Neulasta Before using this medication, tell your doctor if
- are taking lithium (Eskalith, Lithobid, Lithane,
- are undergoing radiation or chemotherapy.
You may not be able to use Neulasta or you may require
special monitoring if you are taking any of the medications
other than those listed here may also interact with Neulasta.
Talk to your doctor and pharmacist before taking any prescription
or over-the-counter medicines, including vitamins, minerals,
and herbal products.