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Paraplatin

What is Paraplatin

Paraplatin is an antineoplastic medication. Paraplatin interferes with the growth of cancer cells and slows their growth and spread in the body.

Paraplatin is used to treat ovarian cancer and many other types of cancer.

Paraplatin may also be used for purposes other than those listed in this medication guide.

General medical information about Paraplatin

Paraplatin should only be administered under the supervision of a qualified healthcare provider experienced in the use of cancer chemotherapeutic agents.

Serious side effects have been reported with the use of Paraplatin including: allergic reactions (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); kidney damage (little or no urine production, blood in the urine); hearing loss or ringing in the ears; decreased bone marrow function and blood problems (extreme fatigue; easy bruising or bleeding; black, bloody or tarry stools; or fever, chills, or signs of infection); severe nausea, vomiting, diarrhea, and loss of appetite; and others. Talk to your doctor about the possible side effects from treatment with Paraplatin.

What you should discuss with your doctor before using Paraplatin

Do not use Paraplatin without first talking to your doctor if you have
- kidney disease;
- a bleeding problem;
- poor bone marrow function;
- hearing impairment; or
- an allergy to platinum, platinum-containing products, or mannitol.

The use of Paraplatin may be dangerous if you have any of the conditions listed above.

Paraplatin is in the FDA pregnancy category D. This means that Paraplatin is known to be harmful to an unborn baby. Do not use Paraplatin without first talking to your doctor if you are pregnant or could become pregnant during treatment. Discuss with your doctor the appropriate use of birth control during treatment with Paraplatin if necessary.

It is not known whether Paraplatin passes into breast milk. Breast-feeding should be avoided during treatment with Paraplatin.

How should you use Paraplatin

Paraplatin should only be administered under the supervision of a qualified healthcare provider experienced in the use of cancer chemotherapeutic agents.

Your doctor will determine the correct amount and frequency of treatment with Paraplatin depending upon the type of cancer being treated and other factors. Talk to your doctor if you have any questions or concerns regarding the treatment schedule.

Adequate hydration is important during treatment with Paraplatin. Your doctor may prescribe the administration of intravenous fluids and/or recommend additional fluid intake by mouth during treatment.

Your doctor will probably want you to have regularly scheduled blood tests and other medical evaluations during treatment with Paraplatin to monitor progress and side effects.

Your healthcare provider will store Paraplatin as directed by the manufacturer. If you are storing Paraplatin at home, follow the directions provided by your healthcare provider.

If you miss a dose:

Contact your doctor if you miss a dose of Paraplatin.

What happens if you overdose:

If for any reason an overdose of Paraplatin is suspected, seek emergency medical attention or contact your healthcare provider immediately.

Symptoms of a Paraplatin overdose tend to be similar to side effects caused by the medication, although often more severe.

What should you avoid while using Paraplatin

Paraplatin can lower the activity of your immune system making you susceptible to infections. Avoid contact with people who have colds, the flu, or other contagious illnesses and do not receive vaccines that contain live strains of a virus (e.g., live oral polio vaccine) during treatment with Paraplatin. In addition, avoid contact with individuals who have recently been vaccinated with a live vaccine. There is a chance that the virus can be passed on to you.

Possible side effects of Paraplatin

If you experience any of the following serious side effects from Paraplatin, contact your doctor immediately or seek emergency medical attention:
- an allergic reaction (including difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
- kidney damage (little or no urine production, blood in the urine);
- decreased bone marrow function and blood problems (extreme fatigue; easy bruising or bleeding; black, bloody or tarry stools; or fever, chills, or signs of infection);
- severe nausea, vomiting, and loss of appetite; or
- blurred vision, altered color perception, temporary blindness, and other visual problems.

Other, less serious side effects may be more likely to occur. Continue taking Paraplatin and talk to your doctor if you experience:
- hearing loss or ringing in the ears;
- numbness or tingling;
- weakness;
- mild to moderate nausea, vomiting, or loss of appetite; or
- hair loss.

Side effect other than those listed here have also been reported. Discuss with your doctor any side effect that occurs during treatment with Paraplatin.

What other drugs will affect Paraplatin

Do not receive "live" vaccines during treatment with Paraplatin. Administration of a live vaccine may be dangerous during treatment with Paraplatin.

Other medications may interact with Paraplatin. Talk to your doctor and pharmacist before taking any other prescription or over-the-counter medicines, including vitamins, minerals, and herbal products, during treatment with Paraplatin.

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