What is Pravachol
blocks the production of cholesterol (a type of fat) in the
is used to reduce the amounts of LDL (bad) cholesterol, total
cholesterol, triglycerides (another type of fat), and apolipoprotein
B (a protein needed to make cholesterol) in your blood. These
actions are important in reducing the risk of hardening of
the arteries, which can lead to heart attacks, stroke, and
peripheral vascular disease.
may also be used for purposes other than those listed in this
General medical information about Pravachol
Do not take Pravachol without first talking to your
doctor if you have liver disease.
Alcohol and Pravachol
can both damage your liver. Discuss with your doctor the
amount of alcohol that you drink so that it can be determined
if Pravachol is the best choice for lowering your cholesterol.
Do not take Pravachol if you are pregnant, if you
are planning a pregnancy, or if you are breast-feeding a
Contact your doctor immediately if you experience
unexplained muscle pain, tenderness, or weakness, especially
if it is accompanied by a fever, flu-like symptoms, or yellowing
of your skin or eyes.
Who should not take Pravachol Do not take Pravachol without first talking to your
doctor if you have liver disease.
Before taking Pravachol,
tell your doctor if you
- have kidney disease,
drink alcoholic beverages,
- have a chronic muscular
- have a blood disorder.
may not be able to take Pravachol, or you may require a
dosage adjustment or special monitoring during treatment
if you have any of the conditions listed above.
is in the FDA pregnancy category X. This means that Pravachol
will cause birth defects if it is taken during pregnancy.
Cholesterol is very important for the proper development
of a baby. Do not take Pravachol if you are pregnant or
are planning a pregnancy.
Pravachol passes into breast
milk and can harm a nursing infant. Do not take Pravachol
if you are breast-feeding a baby.
Pravachol is not
approved for use by children younger than 18 years of age.
How should take Pravachol Take Pravachol exactly as directed by your doctor.
If you do not understand these directions, ask your pharmacist,
nurse, or doctor to explain them to you.
dose with a full glass of water.
For the greatest
effect, Pravachol is usually taken at bedtime or with an
evening meal. It may also be taken several times a day.
Follow your doctor's instructions.
Your doctor may
want to monitor your liver function with blood tests before
starting treatment with Pravachol and at twelve weeks after
both the start of your treatment and any increase in dose.
Depending on the results of these tests, your doctor can
determine how much monitoring you will require.
a low-fat, low-cholesterol diet. To see beneficial effects
from Pravachol, avoid fatty, high-cholesterol foods.
Do not stop taking Pravachol without first talking to your
doctor. It may be weeks or months before beneficial effects
are seen from this medication.
Store Pravachol at
room temperature away from moisture and heat.
If you miss a dose: Take the missed dose as soon as you remember. However,
if it is almost time for your next dose, skip the missed
dose and take only your next regularly scheduled dose. Do
not take a double dose of this medication.
What happens if you overdose: Seek emergency medical attention.
of a Pravachol overdose include nausea, diarrhea, stomach
distress, and indigestion.
Avoid while taking Pravachol Alcohol and Pravachol can both damage your liver.
Discuss with your doctor the amount of alcohol that you
drink so that it can be determined if Pravachol is the best
choice for lowering your cholesterol.
Possible side effects of Pravachol If you experience any of the following serious side
effects, stop taking Pravachol and call your doctor immediately:
- an allergic reaction (difficulty breathing; closing
of your throat; swelling of your lips, tongue, or face;
- muscle aches, pain, or weakness;
- decreased urine
or rust-colored urine;
- blurred vision; or
yellowing of your skin or eyes.
Other, less serious
side effects may be more likely to occur. Continue to take
Pravachol and talk to your doctor if you experience
gas, bloating, nausea, stomach upset, heartburn, abdominal
pain, constipation, or diarrhea;
- a cough;
Side effects other
than those listed here may also occur. Talk to your doctor
about any side effect that seems unusual or that is especially
What other drugs will affect Pravachol Do not take Pravachol without first talking to your
doctor if you are taking any of the following medicines:
- cyclosporine (Sandimmune, Neoral);
- niacin (Nicolar, Nicobid, others); or
- clarithromycin (Biaxin);
(E-Mycin, E.E.S., Ery-Tab, Ilotycin, Eryc, PCE, Ilosone,
The medications listed above may interact
with Pravachol and damage your muscles.
Pravachol, tell your doctor if you are taking any of the
- other cholesterol-lowering
drugs such as cholestyramine (Questran) or colestipol (Colestid);
- warfarin (Coumadin).
You may require
a dosage adjustment or special monitoring during treatment
if you are taking any of the medicines listed above.
other than those listed here may also interact with Pravachol.
Talk to your doctor and pharmacist before taking any prescription
or over-the-counter medicines.