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Relafen

What is Relafen

Relafen is in a class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Relafen works by reducing hormones that cause inflammation and pain in the body.

Relafen is used to reduce the pain, inflammation, and stiffness caused by osteoarthritis and rheumatoid arthritis.

Relafen may also be used for purposes other than those listed in this medication guide.

General medical information about Relafen

Take Relafen with food, milk, or an antacid to lessen stomach upset.

Remaining upright (sitting or standing) for 15 to 30 minutes after each dose may prevent irritation of the esophagus (throat).

If you drink more than three alcoholic beverages a day, Relafen may increase the risk of stomach bleeding.

What you should find out before taking Relafen

Before taking Relafen, tell your doctor if you
- have an allergy to aspirin or any other NSAIDs,
- have an ulcer or bleeding in the stomach,
- drink more than three alcoholic beverages a day,
- have liver or kidney disease,
- have a coagulation (bleeding) disorder,
- have congestive heart failure,
- have fluid retention,
- have heart disease, or
- have high blood pressure.

You may not be able to take Relafen, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.

Relafen is in the FDA pregnancy category C. This means that it is not known whether it will be harmful to an unborn baby. Relafen should not be taken late in pregnancy (the third trimester) because a similar drug is known to affect the baby's heart. Do not take Relafen without first talking to your doctor if you are pregnant or could become pregnant during treatment.

It is not known whether Relafen passes into breast milk Do not take this medicine without first talking to your doctor if you are breast-feeding a baby.

How should take Relafen

Take Relafen exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water.

Taking Relafen with food, milk, or an antacid may lessen stomach upset.

Remaining upright (sitting or standing) for 15 to 30 minutes after each dose may prevent irritation of the esophagus (throat).

Store Relafen at room temperature away from moisture and heat.

If you miss a dose:

Take the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose.

What happens if you overdose:

Seek emergency medical attention.

Symptoms of a Relafen overdose include nausea, vomiting, stomach pain, dizziness, drowsiness, headache, ringing in the ears, blurred vision, seizures, sweating, numbness or tingling, little or no urine production, and slow breathing.

Avoid while taking Relafen

Avoid prolonged exposure to sunlight. Relafen may increase the sensitivity of the skin to sunlight. Use a sunscreen and wear protective clothing when exposure to the sun is unavoidable.

If you drink more than three alcoholic beverages a day, Relafen may increase the risk of stomach bleeding.

Possible side effects of Relafen

If you experience any of the following serious side effects, stop taking Relafen and seek medical treatment or call your doctor immediately:
- an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
- muscle cramps, numbness, or tingling;
- ulcers (open sores) in the mouth;
- rapid weight gain (fluid retention);
- seizures;
- black, bloody or tarry stools
- blood in the urine or vomit;
- decreased hearing or ringing in the ears
- jaundice (yellowing of the skin or eyes); or
- abdominal cramping, indigestion, or heartburn.

Other, less serious side effects may be more likely to occur. Continue to take Relafen and talk to your doctor if you experience
- dizziness or headache;
- nausea, gaseousness, diarrhea, or constipation;
- depression;
- fatigue or weakness;
- dry mouth; or
- irregular menstrual periods.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect Relafen

Before taking Relafen, tell your doctor if you are taking any of the following drugs:
- another nonsteroidal anti-inflammatory drug (NSAID) such as ibuprofen (Motrin, Rufen, others), ketoprofen (Orudis, Orudis KT, Oruvail), naproxen (Naprosyn, Aleve, Anaprox), diclofenac (Voltaren, Cataflam), etodolac (Lodine), fenoprofen (Nalfon), flurbiprofen (Ansaid), indomethacin (Indocin), ketorolac (Toradol), oxaprozin (Daypro), piroxicam (Feldene), sulindac (Clinoril), tolmetin (Tolectin), celecoxib (Celebrex), valdecoxib (Bextra), or rofecoxib (Vioxx);
- aspirin or another salicylate (forms of aspirin) such as salsalate (Disalcid), choline salicylate, and magnesium salicylate (watch the aspirin content of other over-the-counter products such as cough, cold, and allergy medicines);
- a diuretic (water pill) such as hydrochlorothiazide (HCTZ, Hydrodiuril, others), chlorothiazide (Diuril, others), chlorthalidone (Thalitone), bumetanide (Bumex), ethacrynic acid (Edecrin), furosemide (Lasix), spironolactone (Aldactone), and amiloride (Midamor);
- an angiotensin-converting-enzyme (ACE) inhibitor such as benazepril (Lotensin), captopril (Capoten), enalapril (Vasotec), fosinopril (Monopril), lisinopril (Prinivil, Zestril), moexipril (Univasc), quinapril (Accupril), ramipril (Altace), and others;
- a beta-blockers such as acebutolol (Sectral), metoprolol (Lopressor), propranolol (Inderal), atenolol (Tenormin), carteolol (Cartrol), and others;
- an anticoagulant such as warfarin (Coumadin);
- a steroid such as prednisone (Deltasone) or methylprednisolone (Medrol);
- an oral anti-diabetic drug such as glipizide (Glucotrol) and glyburide (Micronase, Diabeta);
- lithium (Eskalith, Lithobid, others); or
- cyclosporine (Sandimmune, Neoral).

You may require a dosage adjustment or special monitoring during treatment if you are taking any of the medications listed above.

Drugs other than those listed here may also interact with Relafen. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products.

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A
abilify accupril accutane acetaminophen aciphex actifed actonel actos acyclovir adalat adderall adipex advair advil albuterol alesse aleve allegra allopurinol amaryl ambien amiodarone amitriptyline amoxicillin amoxil amphetamine anacin aprazolam aricept asacol aspirin atenolol ativan atorvastatin atrovent augmentin avandia avapro avastin avelox azmacort
B
baclofen
bactrim bactroban baycol benadryl bextra biaxin boniva bontril buspar buspirone
C
caduet campral camptosar capoten captopril cardizem cardura carisoprodol casodex catapress cefzil celebrex celexa cellcept cephalexin cialis cipro ciprodex clarinex claritin climara clindamycin clonazepam clonidine codeine codeprex combivent combivir concerta copaxone coreg coricidin cotrim coumadin cozaar crestor cubicin cyclobenzaprine cymbalta
D
darvocet demerol depakote desogen detrol dextromethorphan diazepam diclofenac didrex diflucan digoxin dilantin diltiazem dimetapp diovan diprivan ditropan doxazosin doxycycline drixoral duragesic dyazide
E
effexor elavil elocon eloxatin emend enalapril enbrel endocet engerix-b entex epogen epzicom erbitux ertaczo ery-tab erythromycin estradiol evista 
F
fabrazyme famotidine fazaclo fenofibrate fioricet fiorinal flexeril flomax flonase flovent fluoxetine fosamax fosrenol furosemide  
G
gabapentin gamimune gemfibrozil gemzar glipizide glucophage glucotrol glucovance glyburide glyburide guaifenesin guaifenex 
H
herceptin humalog humira hydroxyzine hyzaar  
I
ibuprofen imdur imitrex imodium inderal insulin integrilin iressa 
K
kaletra keflex kenalog keppra ketek klonopin kytril  
L
lamictal lamisil lanoxin lantus lasix lescol levaquin levitra levothyroxine levoxyl lexapro lidoderm lipitor lisinopril lithium lorazepam lortab lotensin lotrel lotrisone lovenox lupron luveris  
M
macrobid magnevist meclizine medroxyprogesterone meridia metformin methadone methamphetamine methotrexate methylphenidate methylprednisolone metoclopramide metoprolol metronidazole miacalcin minocycline mobic monopril morphine motrin myfortic  
N
naproxen nasacort nasonex natrecor neulasta neupogen neurontin nexium nifedipine nitrofurantoin norco nortriptyline norvasc  
O
omeprazole omnicef orthovisc oxybutynin oxycodone oxycontin oxytrol  
P
paraplatin patanol paxil pegasys penicillin pepcid percocet percodan percogesic phendimetrazine phenergan phentermine phenytoin plavix plendil potassium pravachol prednisone premarin prempro prevacid prilosec prinivil procrit promethazine propecia propofol propoxyphene propranolol protonix proventil provigil prozac pseudoephedrine pulmicort  
R
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S
sanctura seasonale sensipar serevent seroquel serzone singulair skelaxin soma somavert sonata spiriva spironolactone strattera striant sustiva synagis synthroid 
T
tamoxifen tavist taxol taxotere tegretol temazepam tenormin tenuate tequin terazosin tetracycline tiazac tindamax titralac tobradex topamax toprol tramadol trazodone triamcinolone triaminic triamterene tricor trileptal trimox triphasil trizivir truvada tylenol 
U
ultane ultracet ultram uroxatral
V
valium valtrex vaniqa vasotec velcade verapamil viagra vicodin vicoprofen vidaza viracept viread vytorin  
W
warfarin wellbutrin  
X
xalatan xanax xenical xifaxan xolair xopenex xyrem  
Y
yasmin 
Z
zanaflex zantac zavesca zelnorm zemplar zerit zestoretic zestril zetia ziac zithromax zocor zofran zoladex zoloft zometa zorbtive zosyn zovirax zyrtec zyvox