What is Striant
is a naturally occurring "male" sex hormone necessary
for many processes in the body.
is used to treat men with low testosterone levels.
may also be used for purposes other than those listed in this
General medical information about Striant
Notify your doctor if you experience nausea; vomiting;
swelling of the ankles; changes in skin color; too frequent
or prolonged erections; breathing disturbances, including
those associated with sleep; or yellowing of the skin or
Notify your doctor if a female partner experiences
male-pattern baldness, excessive body hair growth, an increase
in acne, menstrual irregularities, or signs of masculinity.
What you should discuss with your doctor before
using Striant Do not use Striant if you have cancer of the breast
or prostate. Testosterone may worsen some cancers of these
Before using Striant, tell your doctor if you have:
- sleep apnea or if you
have risk factors for sleep apnea (e.g., obesity, chronic
- heart disease; or
disease or kidney disease.
You may not be able to
use Striant, or you may need a dosage adjustment or special
monitoring if you have any of the conditions listed above.
Striant is not approved for use by women and must
not be used by women. Striant is in the FDA pregnancy category
X. This means that testosterone is known to cause birth
defects in an unborn baby. Do not use Striant if you are
pregnant or could become pregnant during treatment.
Striant is not approved for use by women and must not be
used by women. It is not known whether testosterone from
the buccal system will pass into breast milk.Do not use
Striant if you are breast-feeding a baby.
65 years of age that use Striant may be at increased risk
for the development of prostatic enlargement or cancer.
You may not be able to use buccal system testosterone, or
you may require a lower dose or special monitoring.
How should you use Striant Use Striant exactly as directed by your doctor. If
you do not understand these directions, ask your pharmacist,
nurse, or doctor to explain them to you.
To use the
- Hold one system with the flat
side on your fingertip. Place the curved side onto your
gum, as high as possible above the left or right incisor
tooth. Hold your finger on the outside of your lip over
the system for 30 seconds to ensure the system is attached
to the gum. If the system sticks to the cheek and not the
gum, this is acceptable.
- The system should remain
in place for 12 hours. To remove the system, move it slightly
toward the back or front of the mouth then slide it down
toward the teeth from removal. With each new application,
rotate sides of the mouth. Check to see that the system
is in place after eating, drinking, brushing the teeth,
or using mouthwash.
- If a system falls off before
8 hours of use, remove it and replace it with a new system
in the same place. Change the system and rotate sides of
the mouth 12 hours after application of the original system.
If a system falls off after 8 hours but before 12 hours
of use, remove the system and replace it with a new system
above the opposite incisor. This will serve as the second
dose for the day.
Your doctor may want to perform
tests to monitor the amount of testosterone in the body,
liver function, prostate function, or other factors during
treatment with Striant.
It is important to use Striant
regularly to get the most benefit.
Dispose of all
used systems properly, out of the reach of children and
Store Striant at room temperature away from
moisture and heat.
If you miss a dose: Apply the next system as soon as you remember. Do
not use two doses simultaneously, unless otherwise directed
by your doctor.
What happens if you overdose: An overdose of Striant is not likely to threaten
life. If you do suspect an overdose, or if a system has
been ingested, call an emergency room or poison control
center for advice.
What should you avoid while using Striant Regularly inspect the gum
Where the Striant is applied.
Promptly report any changes to your doctor or dentist.
Possible side effects of Striant If you experience any of the following serious side
effects, stop using Striant and seek emergency medical attention
or contact your doctor immediately:
- an allergic
reaction (difficulty breathing; closing of the throat; swelling
of the lips, tongue, or face; or hives);
- changes in skin color;
of the ankles;
- breathing disturbances, including
those associated with sleep;
- too frequent or prolonged
- liver damage (yellowing of the skin
or eyes, nausea, abdominal pain or discomfort, unusual bleeding
or bruising, or severe fatigue).
Other, less serious
side effects may be more likely to occur. Continue to use
Striant and talk to your doctor if you experience
irritation or changes in the gum at the system application
- emotional changes;
- increased blood
- decreased interest in sex;
in blood cholesterol or number of red blood cells (detected
by blood tests);
- prostate changes or difficulty
- enlarged, swollen or tender breasts;
Notify your doctor if a female
partner experiences male-pattern baldness, excessive body
hair growth, an increase in acne, menstrual irregularities,
or signs of masculinity.
Side effects other than
those listed here may also occur. Talk to your doctor about
any side effect that seems unusual or that is especially
What other drugs will affect Striant Before using Striant, tell your doctor if you are
taking any of the following medicines:
- insulin or an oral diabetes medication
such as glipizide (Glucotrol), glyburide (Diabeta, Micronase,
Glynase), repaglinide (Prandin), rosiglitazone (Avandia),
pioglitazone (Actos), and others;
- propranolol (Inderal,
Inderal LA, others); or
- a corticosteroid such as
hydrocortisone (Cortef, Hydrocortone, Solu-Cortef), dexamethasone
(Decadron, Hexadrol others), methylprednisolone (Depo-Medrol,
Medrol, Solu-Medrol), prednisolone (Prelone Pediapred),
prednisone (Deltasone, Orasone, others), and others.
You may not be able to use Striant, or you may require a
dosage adjustment or special monitoring during treatment
if you are taking any of the medicines listed above.
other than those listed here may also interact with Striant.
Talk to your doctor and pharmacist before taking any prescription
or over-the-counter medicines, including vitamins, minerals,
and herbal products.