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Trazodone

What is Trazodone

Trazodone is an antidepressant medication. It works by changing the actions of chemicals in the brain.

Trazodone is used to relieve symptoms of depression such as feelings of sadness, worthlessness, or guilt; loss of interest in daily activities; changes in appetite; tiredness; sleeping too much; insomnia; and thoughts of death or suicide.

Trazodone may also be used for purposes other than those listed in this medication guide.

General medical information about Trazodone

Stop taking Trazodone and call your doctor immediately if you experience a prolonged (4 hours or longer), painful, or inappropriate erection. This could lead to a serious condition requiring surgery.

Use caution when driving, operating machinery, or performing other hazardous activities. Trazodone may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.

Dizziness may be more likely to occur when you rise from a sitting or lying position. Rise slowly to prevent dizziness and a possible fall.

Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while taking Trazodone.

Do not stop taking Trazodone without first talking to your doctor, even if you begin to feel better. It may be several weeks before your symptoms begin to improve, and you may require continuous treatment for quite some time.

What you should find out before taking Trazodone

Do not take Trazodone if you have had a heart attack in the past 6 weeks. You may also require special monitoring during treatment if you have any type of heart disease, including a past heart attack, high blood pressure, irregular heartbeats, or chest pain (angina).

Trazodone is in the FDA pregnancy category C. This means that it is not known whether Trazodone will be harmful to an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant or could become pregnant during treatment.

It is not known whether Trazodone passes into breast milk. Do not take Trazodone without first talking to your doctor if you are breast-feeding a baby.

How should take Trazodone

Take Trazodone exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain the instructions to you.

Take each dose with a full glass of water.

Take Trazodone with a meal or a light snack. Food increases the amount of medicine that is absorbed by the body and it may help to decrease dizziness.

Do not stop taking Trazodone without first talking to your doctor, even if you begin to feel better. It may be several weeks before your symptoms begin to improve, and you may require continuous treatment for quite some time.

Store Trazodone at room temperature away from moisture and heat.

If you miss a dose:

Take the missed dose as soon as you remember. However, if it is almost time for the next regularly scheduled dose, skip the missed dose and take only the next one as directed. Do not take a double dose of this medication.

What happens if you overdose:

Seek emergency medical attention.

Symptoms of a Trazodone overdose include drowsiness, nausea, vomiting, seizures, an irregular heart beat, difficulty breathing, painful erection, and death.

Avoid while taking Trazodone

Use caution when driving, operating machinery, or performing other hazardous activities. Trazodone may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.

Dizziness may be more likely to occur when you rise from a sitting or lying position. Rise slowly to prevent dizziness and a possible fall.

Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while taking Trazodone.

Possible side effects of Trazodone

If you experience any of the following serious side effects, stop taking Trazodone and seek emergency medical attention or contact your doctor immediately:
- an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
- a prolonged (4 hours or longer), painful, or inappropriate erection; or
- an irregular heartbeat or chest pains.

Other, less serious side effects may be more likely to occur. Continue to take Trazodone and talk to your doctor if you experience
- dizziness or drowsiness;
- headache;
- insomnia or vivid dreams;
- dry mouth, upset stomach, nausea, or vomiting;
- diarrhea or constipation;
- tremors (shaking); or
- blurred vision.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect Trazodone

Before taking Trazodone, tell your doctor if you are taking any of the following medications:
- digoxin (Lanoxin, Lanoxicaps);
- phenytoin (Dilantin);
- a monoamine oxidase (MAO) inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate); or
- warfarin (Coumadin).

You may not be able to take Trazodone, or you may require special monitoring during treatment if you are taking any of the medicines listed above.

Drugs other than those listed here may also interact with Trazodone. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products.

All prescription drugs:

A
abilify accupril accutane acetaminophen aciphex actifed actonel actos acyclovir adalat adderall adipex advair advil albuterol alesse aleve allegra allopurinol amaryl ambien amiodarone amitriptyline amoxicillin amoxil amphetamine anacin aprazolam aricept asacol aspirin atenolol ativan atorvastatin atrovent augmentin avandia avapro avastin avelox azmacort
B
baclofen
bactrim bactroban baycol benadryl bextra biaxin boniva bontril buspar buspirone
C
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D
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E
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F
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G
gabapentin gamimune gemfibrozil gemzar glipizide glucophage glucotrol glucovance glyburide glyburide guaifenesin guaifenex 
H
herceptin humalog humira hydroxyzine hyzaar  
I
ibuprofen imdur imitrex imodium inderal insulin integrilin iressa 
K
kaletra keflex kenalog keppra ketek klonopin kytril  
L
lamictal lamisil lanoxin lantus lasix lescol levaquin levitra levothyroxine levoxyl lexapro lidoderm lipitor lisinopril lithium lorazepam lortab lotensin lotrel lotrisone lovenox lupron luveris  
M
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N
naproxen nasacort nasonex natrecor neulasta neupogen neurontin nexium nifedipine nitrofurantoin norco nortriptyline norvasc  
O
omeprazole omnicef orthovisc oxybutynin oxycodone oxycontin oxytrol  
P
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R
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S
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T
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U
ultane ultracet ultram uroxatral
V
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W
warfarin wellbutrin  
X
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Y
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Z
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