prescription drugs
Free drug information service 
All available medical information about prescription drugs 

Velcade

What is Velcade

Velcade interferes with the growth of some cancer cells.

Velcade is used to in the treatment of the blood cancer multiple myeloma.

Velcade may also be used for purposes other than those listed in this medication guide.

General medical information about Velcade

Velcade should only be administered under the supervision of a qualified healthcare provider experienced in the use of cancer chemotherapeutic agents.

Because Velcade is known to cause birth defects in an unborn baby, women of childbearing age should not become pregnant during treatment.

Use caution when driving, operating machinery, or performing other hazardous activities. Velcade may cause drowsiness, dizziness, fainting, or blurred or double vision. If you experience any of these side effects, avoid hazardous activities.

Dizziness may be more likely to occur when rising from sitting or lying down. Rise slowly to minimize dizziness and prevent a possible fall.

Treatment with Velcade may cause dehydration due to vomiting and/or diarrhea. Follow your healthcare provider's instructions for maintaining adequate fluid intake to reduce the chance of dehydration. Contact your healthcare provider if you experience dizziness, light headedness, or fainting, as these may be signs of dehydration.

Peripheral neuropathy (nerve problems) is one of the potential side effects of treatment with Velcade. Contact your healthcare provider immediately if you experience new or worsening symptoms of peripheral neuropathy such as burning sensation, numbness, increased or decreased sensation, pain, or discomfort.

Velcade can lower the activity of the immune system making you susceptible to infections. Avoid contact with people who have colds, the flu, or other contagious illnesses and do not receive vaccines that contain live strains of a virus (e.g., live oral polio vaccine) during treatment with Velcade. In addition, avoid contact with individuals who have recently been vaccinated with a live vaccine. There is a chance that the virus can be passed on to you. Contact your doctor if you develop fever, chills, sore throat, or other symptoms of a cold or flu or painful or difficult urination.

What you should find out before taking Velcade

Do not take Velcade without first talking to your doctor if you have
- liver disease;
- kidney disease;
- a bleeding or blood clotting disorder;
- a low level of platelets or white or red blood cells;
- a history of low blood pressure or if you are taking medicine to lower blood pressure; or
- peripheral neuropathy (nerve problems such as burning sensation, numbness, increased or decreased sensation, pain, or discomfort).

You may not be able to take Velcade, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.

Velcade is in the FDA pregnancy category D. This means that it is known to be harmful to an unborn baby.Do not take this medication if you are pregnant. Pregnancy should be avoided during treatment with Velcade.

It is not known whether Velcade passes into breast milk. Do not take Velcade without first talking to your doctor if you are breast-feeding a baby.

How should take Velcade

Velcade should only be administered under the supervision of a qualified healthcare provider experienced in the use of cancer chemotherapeutic agents.

Velcade is administered by intravenous injection (into a vein). It is usually administered in a hospital or clinic setting by a healthcare professional.

Your doctor will determine the correct amount and frequency of treatment with Velcade depending upon the type of cancer being treated and other factors. Talk to your doctor if you have any questions or concerns regarding the treatment schedule.

Your doctor will probably want you to have blood tests and other medical evaluations during treatment with Velcade to monitor progress and side effects.

Your healthcare provider will store Velcade as directed by the manufacturer. If you are storing Velcade at home, follow the directions provided by your healthcare provider.

If you miss a dose:

It is important not to miss a dose of Velcade. Contact your doctor if you are unable to keep an appointment.

What happens if you overdose:

Seek emergency medical attention if an overdose of Velcade is suspected.

Symptoms of a Velcade overdose are not known.

Avoid while taking Velcade

Because Velcade is known to cause birth defects in an unborn baby, women of childbearing age should not become pregnant during treatment.

Use caution when driving, operating machinery, or performing other hazardous activities. Velcade may cause drowsiness, dizziness, fainting, or blurred or double vision. If you experience any of these side effects, avoid hazardous activities.

Dizziness may be more likely to occur when rising from sitting or lying down. Rise slowly to minimize dizziness and prevent a possible fall.

Treatment with Velcade may cause dehydration due to vomiting and/or diarrhea. Follow your healthcare provider's instructions for maintaining adequate fluid intake to reduce the chance of dehydration. Contact your healthcare provider if you experience dizziness, light headedness, or fainting, as these may be signs of dehydration.

Tell your doctor and dentist that you are taking Velcade before having surgery or dental work. You may bleed more easily or be more likely to get an infection while taking Velcade.

Velcade can lower the activity of the immune system making you susceptible to infections. Avoid contact with people who have colds, the flu, or other contagious illnesses and do not receive vaccines that contain live strains of a virus (e.g., live oral polio vaccine) during treatment with Velcade. In addition, avoid contact with individuals who have recently been vaccinated with a live vaccine. There is a chance that the virus can be passed on to you. Contact your doctor if you develop fever, chills, sore throat, or other symptoms of a cold or flu or painful or difficult urination.

Possible side effects of Velcade

If you experience any of the following serious side effects, seek emergency medical attention or contact your doctor as soon as possible:
- an allergic reaction (shortness of breath; closing of the throat; difficulty breathing; swelling of the lips, face, or tongue; or hives);
- unusual bruising or bleeding, nosebleeds, pinpoint red spots on the skin, or black, bloody or tarry stools (may be signs of low platelets in the blood);
- new or worsening nerve problems such as a burning sensation, numbness, increased or decreased sensation, pain, or discomfort (may indicate peripheral neuropathy);
- fever, chills, sore throat, other symptoms of a cold or flu or painful or difficult urination (may indicate an infection);
- fainting;
- diarrhea or vomiting; or
- a skin rash.

Other less serious side effects may occur more frequently. Continue to take Velcade and talk to your doctor if you experience:
- nausea or decreased appetite;
- anxiety;
- headache;
- blurred or double vision;
- dizziness or light headedness;
- tiredness or weakness; or
- muscle or bone pain.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect Velcade

Many medications may interact with Velcade. Do not take any other prescription or over-the-counter medicines, including vitamins and minerals and herbal supplements, without first talking to your healthcare provider.

All prescription drugs:

A
abilify accupril accutane acetaminophen aciphex actifed actonel actos acyclovir adalat adderall adipex advair advil albuterol alesse aleve allegra allopurinol amaryl ambien amiodarone amitriptyline amoxicillin amoxil amphetamine anacin aprazolam aricept asacol aspirin atenolol ativan atorvastatin atrovent augmentin avandia avapro avastin avelox azmacort
B
baclofen
bactrim bactroban baycol benadryl bextra biaxin boniva bontril buspar buspirone
C
caduet campral camptosar capoten captopril cardizem cardura carisoprodol casodex catapress cefzil celebrex celexa cellcept cephalexin cialis cipro ciprodex clarinex claritin climara clindamycin clonazepam clonidine codeine codeprex combivent combivir concerta copaxone coreg coricidin cotrim coumadin cozaar crestor cubicin cyclobenzaprine cymbalta
D
darvocet demerol depakote desogen detrol dextromethorphan diazepam diclofenac didrex diflucan digoxin dilantin diltiazem dimetapp diovan diprivan ditropan doxazosin doxycycline drixoral duragesic dyazide
E
effexor elavil elocon eloxatin emend enalapril enbrel endocet engerix-b entex epogen epzicom erbitux ertaczo ery-tab erythromycin estradiol evista 
F
fabrazyme famotidine fazaclo fenofibrate fioricet fiorinal flexeril flomax flonase flovent fluoxetine fosamax fosrenol furosemide  
G
gabapentin gamimune gemfibrozil gemzar glipizide glucophage glucotrol glucovance glyburide glyburide guaifenesin guaifenex 
H
herceptin humalog humira hydroxyzine hyzaar  
I
ibuprofen imdur imitrex imodium inderal insulin integrilin iressa 
K
kaletra keflex kenalog keppra ketek klonopin kytril  
L
lamictal lamisil lanoxin lantus lasix lescol levaquin levitra levothyroxine levoxyl lexapro lidoderm lipitor lisinopril lithium lorazepam lortab lotensin lotrel lotrisone lovenox lupron luveris  
M
macrobid magnevist meclizine medroxyprogesterone meridia metformin methadone methamphetamine methotrexate methylphenidate methylprednisolone metoclopramide metoprolol metronidazole miacalcin minocycline mobic monopril morphine motrin myfortic  
N
naproxen nasacort nasonex natrecor neulasta neupogen neurontin nexium nifedipine nitrofurantoin norco nortriptyline norvasc  
O
omeprazole omnicef orthovisc oxybutynin oxycodone oxycontin oxytrol  
P
paraplatin patanol paxil pegasys penicillin pepcid percocet percodan percogesic phendimetrazine phenergan phentermine phenytoin plavix plendil potassium pravachol prednisone premarin prempro prevacid prilosec prinivil procrit promethazine propecia propofol propoxyphene propranolol protonix proventil provigil prozac pseudoephedrine pulmicort  
R
ranitidine rebetol reglan relafen relpax remeron remicade renagel renova rhinocort riomet risperdal risperidone ritalin rituxan rocephin rogaine roxicet  
S
sanctura seasonale sensipar serevent seroquel serzone singulair skelaxin soma somavert sonata spiriva spironolactone strattera striant sustiva synagis synthroid 
T
tamoxifen tavist taxol taxotere tegretol temazepam tenormin tenuate tequin terazosin tetracycline tiazac tindamax titralac tobradex topamax toprol tramadol trazodone triamcinolone triaminic triamterene tricor trileptal trimox triphasil trizivir truvada tylenol 
U
ultane ultracet ultram uroxatral
V
valium valtrex vaniqa vasotec velcade verapamil viagra vicodin vicoprofen vidaza viracept viread vytorin  
W
warfarin wellbutrin  
X
xalatan xanax xenical xifaxan xolair xopenex xyrem  
Y
yasmin 
Z
zanaflex zantac zavesca zelnorm zemplar zerit zestoretic zestril zetia ziac zithromax zocor zofran zoladex zoloft zometa zorbtive zosyn zovirax zyrtec zyvox