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Xifaxan

What is Xifaxan

Xifaxan is a non-systemic (does not get into bloodstream) antibiotic used to treat diarrhea caused by eating food or drinking fluids that have been contaminated with germs called bacteria.

When you swallow Xifaxan, the drug passes into and remains almost entirely, in your gut and gastrointestinal tract. This differs from how other antibiotics work. Other antibiotics typically pass from the gastrointestinal tract into the bloodstream. Because Xifaxan remains in the gastrointestinal tract, it is not suitable for treating other infections such as chest, sinus, or lung infections caused by bacteria.

Some forms or diarrhea may be caused by viruses and not bacteria. Xifaxan, like all antibiotics, does not kill viruses. You should contact your doctor or healthcare provider if you think your condition is getting worse or not improving after 24 to 48 hours (1 to 2 days) while taking Xifaxan.

Xifaxan may also be used for purposes other than those listed in this medication guide.

General medical information about Xifaxan

Take all of the Xifaxan that has been prescribed for you even if you begin to feel better. Your symptoms may start to improve before the infection is completely treated.

You should not take Xifaxan if you have a fever or have blood in your stool. Talk to your doctor if you have these symptoms.

Some forms or diarrhea may be caused by viruses and not bacteria. Xifaxan, like all antibiotics, does not kill viruses. You should contact your doctor or healthcare provider if you think your condition is getting worse or not improving after 24 to 48 hours (1 to 2 days) while taking Xifaxan.

What you should find out before taking Xifaxan

Before taking Xifaxan, tell your doctor if you have:
- had an allergic reaction to any of the group of antibiotics known as rifamycins such as rifampin (Rifadin, Rimactane) or rifabutin (Mycobutin).
- a fever;
- blood in your stool; or
- a form or diarrhea known as dysentery.

Xifaxan is in the FDA pregnancy category C. This means that it is not known whether it will harm an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant.

It is not known whether Xifaxan passes into breast milk. Do not take this medication without first talking to your doctor if you are breast-feeding a baby.

How should take Xifaxan

Take Xifaxan exactly as directed by your doctor. If you do not understand the instructions, ask your pharmacist, nurse, or doctor to explain them to you.

Xifaxan tablets can be taken with or without food.

You should not take Xifaxan if you have a fever or have blood in your stool. Talk to your doctor if you have these symptoms.

Take all of the Xifaxan that has been prescribed for you even if you begin to feel better. Your symptoms may start to improve before the infection is completely treated.

Store this medication at room temperature away from moisture and heat.

If you miss a dose:

Take the missed dose as soon as you remember. However, if it is almost time for the next regularly scheduled dose, skip the missed dose and take the next one as directed. Do not take a double dose of this medication unless otherwise directed by your doctor.

What happens if you overdose:

Seek emergency medical attention if an overdose is suspected.

Symptoms of an Xifaxan overdose are unknown but may include nausea, vomiting, diarrhea, and abdominal discomfort.

Avoid while taking Xifaxan

Use caution when driving, operating machinery, or performing other hazardous activities. Xifaxan may cause dizziness. If you experience dizziness, avoid these activities.

Possible side effects of Xifaxan

No serious side effects are expected from Xifaxan therapy. Stop taking Xifaxan and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives).

Other, less serious side effects may be more likely to occur. Continue to take Xifaxan and talk to your doctor if you experience
- dizziness or headache;
- flatulence (gas);
- stomach pain;
- sensations of needing to empty the bowel;
- urgent bowel movements;
- constipation;
- fever;
- rash; or
- nausea or vomiting.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect Xifaxan

There are no known interactions between Xifaxan and other medicines, although the possibility exists. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

All prescription drugs:

A
abilify accupril accutane acetaminophen aciphex actifed actonel actos acyclovir adalat adderall adipex advair advil albuterol alesse aleve allegra allopurinol amaryl ambien amiodarone amitriptyline amoxicillin amoxil amphetamine anacin aprazolam aricept asacol aspirin atenolol ativan atorvastatin atrovent augmentin avandia avapro avastin avelox azmacort
B
baclofen
bactrim bactroban baycol benadryl bextra biaxin boniva bontril buspar buspirone
C
caduet campral camptosar capoten captopril cardizem cardura carisoprodol casodex catapress cefzil celebrex celexa cellcept cephalexin cialis cipro ciprodex clarinex claritin climara clindamycin clonazepam clonidine codeine codeprex combivent combivir concerta copaxone coreg coricidin cotrim coumadin cozaar crestor cubicin cyclobenzaprine cymbalta
D
darvocet demerol depakote desogen detrol dextromethorphan diazepam diclofenac didrex diflucan digoxin dilantin diltiazem dimetapp diovan diprivan ditropan doxazosin doxycycline drixoral duragesic dyazide
E
effexor elavil elocon eloxatin emend enalapril enbrel endocet engerix-b entex epogen epzicom erbitux ertaczo ery-tab erythromycin estradiol evista 
F
fabrazyme famotidine fazaclo fenofibrate fioricet fiorinal flexeril flomax flonase flovent fluoxetine fosamax fosrenol furosemide  
G
gabapentin gamimune gemfibrozil gemzar glipizide glucophage glucotrol glucovance glyburide glyburide guaifenesin guaifenex 
H
herceptin humalog humira hydroxyzine hyzaar  
I
ibuprofen imdur imitrex imodium inderal insulin integrilin iressa 
K
kaletra keflex kenalog keppra ketek klonopin kytril  
L
lamictal lamisil lanoxin lantus lasix lescol levaquin levitra levothyroxine levoxyl lexapro lidoderm lipitor lisinopril lithium lorazepam lortab lotensin lotrel lotrisone lovenox lupron luveris  
M
macrobid magnevist meclizine medroxyprogesterone meridia metformin methadone methamphetamine methotrexate methylphenidate methylprednisolone metoclopramide metoprolol metronidazole miacalcin minocycline mobic monopril morphine motrin myfortic  
N
naproxen nasacort nasonex natrecor neulasta neupogen neurontin nexium nifedipine nitrofurantoin norco nortriptyline norvasc  
O
omeprazole omnicef orthovisc oxybutynin oxycodone oxycontin oxytrol  
P
paraplatin patanol paxil pegasys penicillin pepcid percocet percodan percogesic phendimetrazine phenergan phentermine phenytoin plavix plendil potassium pravachol prednisone premarin prempro prevacid prilosec prinivil procrit promethazine propecia propofol propoxyphene propranolol protonix proventil provigil prozac pseudoephedrine pulmicort  
R
ranitidine rebetol reglan relafen relpax remeron remicade renagel renova rhinocort riomet risperdal risperidone ritalin rituxan rocephin rogaine roxicet  
S
sanctura seasonale sensipar serevent seroquel serzone singulair skelaxin soma somavert sonata spiriva spironolactone strattera striant sustiva synagis synthroid 
T
tamoxifen tavist taxol taxotere tegretol temazepam tenormin tenuate tequin terazosin tetracycline tiazac tindamax titralac tobradex topamax toprol tramadol trazodone triamcinolone triaminic triamterene tricor trileptal trimox triphasil trizivir truvada tylenol 
U
ultane ultracet ultram uroxatral
V
valium valtrex vaniqa vasotec velcade verapamil viagra vicodin vicoprofen vidaza viracept viread vytorin  
W
warfarin wellbutrin  
X
xalatan xanax xenical xifaxan xolair xopenex xyrem  
Y
yasmin 
Z
zanaflex zantac zavesca zelnorm zemplar zerit zestoretic zestril zetia ziac zithromax zocor zofran zoladex zoloft zometa zorbtive zosyn zovirax zyrtec zyvox