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Zofran

What is Zofran

Zofran blocks the actions of chemicals in the body that may cause nausea and vomiting.

Zofran is used to prevent nausea and vomiting associated with cancer chemotherapy, radiation therapy, and surgery.

Zofran may also be used for purposes other than those listed in this medication guide.

General medical information about Zofran

The Zofran orally disintegrating tablets (Zofran ODT) can be taken with or without water. Do not remove the tablet from the blister until immediately before taking a dose. Do not try to push the tablet through the foil backing, the tablet may break. With dry hands, peel back the foil backing of one blister and gently remove the tablet. Immediately place the tablet on your tongue where it will dissolve in seconds, then swallow with saliva. Administration with water is not necessary.

Who should not take Zofran

Before taking Zofran, tell your doctor if you have liver disease. You may require a dosage adjustment or special monitoring during treatment.

The Zofran ODT (orally disintegrating tablets) contain phenylalanine. Phenylketonuric patients should be aware that both the 4 mg and 8 mg tablets contain less than 0.03 mg of phenylalanine.

Zofran is in the FDA pregnancy category B. This means that it is not likely to harm an unborn baby. Do not take Zofran without first talking to your doctor if you are pregnant or if you are planning a pregnancy.

It is also not known whether Zofran passes into breast milk. Do not take Zofran without first talking to your doctor if you are breast-feeding a baby.

How should take Zofran

Take Zofran exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each regular tablet with a full glass of water.

The Zofran orally disintegrating tablets (Zofran ODT) can be taken with or without water. Do not remove the tablet from the blister until immediately before taking a dose. Do not try to push the tablet through the foil backing, the tablet may break. With dry hands, peel back the foil backing of one blister and gently remove the tablet. Immediately place the tablet on your tongue

Where it will dissolve in seconds, then swallow with saliva. Administration with water is not necessary.

To ensure that you get a correct dose, measure the liquid form of Zofran with a special dose-measuring spoon or cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one.

Zofran can be taken with or without food.

Store Zofran at room temperature away from moisture and heat.

If you miss a dose:

Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of this medication.

What happens if you overdose:

Seek emergency medical attention.

Symptoms of a Zofran overdose are not well known but might include headache, temporary blindness, constipation, faintness, and heart problems.

Avoid while taking Zofran

There are no restrictions on foods, beverages, or activities during treatment with Zofran unless otherwise directed by your doctor.

Possible side effects of Zofran

If you experience any of the following uncommon but serious side effects, stop taking Zofran and seek emergency medical attention or contact your doctor immediately:
- an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);
- irregular heartbeats; or
- muscle cramps or uncontrollable movements.

Other, less serious side effects may be more likely to occur. Continue to take Zofran and talk to your doctor if you experience:
- headache;
- fatigue, drowsiness, or dizziness;
- anxiety or agitation; or
- diarrhea or constipation.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect Zofran

Zofran has not been reported to interact with other medicines. Talk to your doctor and pharmacist before taking any other prescription or over-the-counter medicines during treatment with Zofran.

All prescription drugs:

A
abilify accupril accutane acetaminophen aciphex actifed actonel actos acyclovir adalat adderall adipex advair advil albuterol alesse aleve allegra allopurinol amaryl ambien amiodarone amitriptyline amoxicillin amoxil amphetamine anacin aprazolam aricept asacol aspirin atenolol ativan atorvastatin atrovent augmentin avandia avapro avastin avelox azmacort
B
baclofen
bactrim bactroban baycol benadryl bextra biaxin boniva bontril buspar buspirone
C
caduet campral camptosar capoten captopril cardizem cardura carisoprodol casodex catapress cefzil celebrex celexa cellcept cephalexin cialis cipro ciprodex clarinex claritin climara clindamycin clonazepam clonidine codeine codeprex combivent combivir concerta copaxone coreg coricidin cotrim coumadin cozaar crestor cubicin cyclobenzaprine cymbalta
D
darvocet demerol depakote desogen detrol dextromethorphan diazepam diclofenac didrex diflucan digoxin dilantin diltiazem dimetapp diovan diprivan ditropan doxazosin doxycycline drixoral duragesic dyazide
E
effexor elavil elocon eloxatin emend enalapril enbrel endocet engerix-b entex epogen epzicom erbitux ertaczo ery-tab erythromycin estradiol evista 
F
fabrazyme famotidine fazaclo fenofibrate fioricet fiorinal flexeril flomax flonase flovent fluoxetine fosamax fosrenol furosemide  
G
gabapentin gamimune gemfibrozil gemzar glipizide glucophage glucotrol glucovance glyburide glyburide guaifenesin guaifenex 
H
herceptin humalog humira hydroxyzine hyzaar  
I
ibuprofen imdur imitrex imodium inderal insulin integrilin iressa 
K
kaletra keflex kenalog keppra ketek klonopin kytril  
L
lamictal lamisil lanoxin lantus lasix lescol levaquin levitra levothyroxine levoxyl lexapro lidoderm lipitor lisinopril lithium lorazepam lortab lotensin lotrel lotrisone lovenox lupron luveris  
M
macrobid magnevist meclizine medroxyprogesterone meridia metformin methadone methamphetamine methotrexate methylphenidate methylprednisolone metoclopramide metoprolol metronidazole miacalcin minocycline mobic monopril morphine motrin myfortic  
N
naproxen nasacort nasonex natrecor neulasta neupogen neurontin nexium nifedipine nitrofurantoin norco nortriptyline norvasc  
O
omeprazole omnicef orthovisc oxybutynin oxycodone oxycontin oxytrol  
P
paraplatin patanol paxil pegasys penicillin pepcid percocet percodan percogesic phendimetrazine phenergan phentermine phenytoin plavix plendil potassium pravachol prednisone premarin prempro prevacid prilosec prinivil procrit promethazine propecia propofol propoxyphene propranolol protonix proventil provigil prozac pseudoephedrine pulmicort  
R
ranitidine rebetol reglan relafen relpax remeron remicade renagel renova rhinocort riomet risperdal risperidone ritalin rituxan rocephin rogaine roxicet  
S
sanctura seasonale sensipar serevent seroquel serzone singulair skelaxin soma somavert sonata spiriva spironolactone strattera striant sustiva synagis synthroid 
T
tamoxifen tavist taxol taxotere tegretol temazepam tenormin tenuate tequin terazosin tetracycline tiazac tindamax titralac tobradex topamax toprol tramadol trazodone triamcinolone triaminic triamterene tricor trileptal trimox triphasil trizivir truvada tylenol 
U
ultane ultracet ultram uroxatral
V
valium valtrex vaniqa vasotec velcade verapamil viagra vicodin vicoprofen vidaza viracept viread vytorin  
W
warfarin wellbutrin  
X
xalatan xanax xenical xifaxan xolair xopenex xyrem  
Y
yasmin 
Z
zanaflex zantac zavesca zelnorm zemplar zerit zestoretic zestril zetia ziac zithromax zocor zofran zoladex zoloft zometa zorbtive zosyn zovirax zyrtec zyvox