What should your doctor know before you receive
He has to know if you have any of these conditions:
low potassium levels in the blood
stomach problems (especially colitis)
an unusual or allergic reaction to Zosyn, other penicillins,
cephalosporin antibiotics, imipenem, foods, dyes, or preservatives
How should you use this medicine
Zosyn is for infusion into a vein. Follow the directions on
the prescription label. Use your doses at regular intervals.
Do not use your medicine more often than directed. Finish
the full course prescribed by your prescriber or health care
professional even if you think your condition is better. Do
not stop using except on your prescriber's advice.
Contact your pediatrician or health care professional regarding
the use of this medicine in children. Special care may be
What drug(s) may interact with Zosyncertain antibiotics given by injection
Tell your prescriber or health care professional: about
all other medicines you are taking including nonprescription
medicines; if you are a frequent user of drinks with caffeine
or alcohol; if you smoke; or if you use illegal drugs. These
can affect the way your medicine works. Check with your
health care professional before stopping or starting any
of your medicines.
What side effects might I notice from receiving Zosyn
Side effects that you should report to your prescriber or
health care professional as soon as possible:
difficulty breathing, wheezing
fever or chills, sore throat
pain, swelling, and irritation at the injection site
red spots on the skin
redness, blistering, peeling, or loosening of the
skin including inside the mouth
severe or watery diarrhea
swelling of face and neck
skin rash, itching
unusual weakness or tiredness
Side effects that usually do not require medical attention
(report to your prescriber or health care professional if
they continue or are bothersome):
What should you watch for while taking Zosyn
Tell your prescriber or health care professional if your
symptoms do not improve in 2 or 3 days.
If you get severe or watery diarrhea, do not treat yourself.
Call your prescriber or health care professional for advice.
If you get a skin rash, do not treat yourself. Call your
prescriber or health care professional for advice.
If you are diabetic and taking large doses of Zosyn, you
may get a false-positive result for sugar in your urine.
Check with your prescriber or health care professional before
you change your diet or the dose of your diabetic medicine.
Where you can keep Zosyn
Keep Zosyn out of the reach of children.
After mixing the injection solution, use within 24 hours
if kept at room temperature; within 1 week if kept in a
refrigerator between 2 degrees and 8 degrees C (59 degrees
and 86 degrees F). Follow the manufacturer's advice on storage
of diluted solutions. Throw away any unused injection solutions.